s179474

• Gene Symbol: Kdm1a
• Gene Name: lysine (K)-specific demethylase 1A
• Gene Aliases: Aof2, Kdm1, RGD1562975
• Chromosome Location: Chr.5: 154909003 - 154965171 on Build Rnor_6.0
• UniGene ID: Rn.203461
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Kdm1a
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001130098.1	NP_001123570.1	12, 13	1688
GenBank mRNA	EF688598.1	-	12, 13	1688

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_001009999, NM_015013, BC048134, AK290328, BC025362, and others.
This siRNA also targets the following transcripts in Mouse: NM_133872, BC059885, AK129170.

Panther Classification:

Molecular Function -

oxidase

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
alternative mRNA splicing, via spliceosome
in utero embryonic development
regulation of transcription from RNA polymerase II promoter
protein demethylation
cell proliferation
regulation of primitive erythrocyte differentiation
positive regulation of neuron projection development
response to organic cyclic compound
pituitary gland development
cerebral cortex development
granulocyte differentiation
negative regulation of protein binding
histone H3-K9 demethylation
histone H3-K4 demethylation
positive regulation of chromatin binding
neuron maturation
negative regulation of sequence-specific DNA binding transcription factor activity
negative regulation of DNA damage response, signal transduction by p53 class mediator
positive regulation of erythrocyte differentiation
positive regulation of megakaryocyte differentiation
positive regulation of cell size
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
guanine metabolic process
positive regulation of hormone biosynthetic process
positive regulation of sequence-specific DNA binding transcription factor activity
negative regulation of histone H3-K4 methylation
negative regulation of histone H3-K9 methylation
muscle cell development
oxidation-reduction process
response to fungicide
cellular response to cAMP
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
positive regulation of neural precursor cell proliferation
positive regulation of stem cell proliferation

Function(s)

RNA polymerase II transcription factor binding
p53 binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
protein binding
transcription factor binding
oxidoreductase activity
enzyme binding
ligand-dependent nuclear receptor transcription coactivator activity
demethylase activity
histone demethylase activity
histone demethylase activity (H3-K4 specific)
histone demethylase activity (H3-K9 specific)
histone demethylase activity (H3-dimethyl-K4 specific)
MRF binding
transcription regulatory region DNA binding
flavin adenine dinucleotide binding
androgen receptor binding