s185974

• Gene Symbol: Tnfaip3
• Gene Name: tumor necrosis factor, alpha-induced protein 3
• Gene Aliases: -
• Chromosome Location: Chr.1: 14401103 - 14412822 on Build Rnor_6.0
• UniGene ID: -
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Tnfaip3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	XM_003748656.3	XP_003748704.2	6	1955

More Information

Panther Classification:

Molecular Function -

cysteine protease

Gene Ontology Categories:

Process(es)

B-1 B cell homeostasis
response to molecule of bacterial origin
regulation of germinal center formation
negative regulation of chronic inflammatory response
protein deubiquitination
negative regulation of protein ubiquitination
negative regulation of NF-kappaB transcription factor activity
response to muramyl dipeptide
negative regulation of interleukin-1 beta production
negative regulation of interleukin-2 production
negative regulation of interleukin-6 production
negative regulation of tumor necrosis factor production
negative regulation of toll-like receptor 3 signaling pathway
negative regulation of toll-like receptor 5 signaling pathway
protein K11-linked deubiquitination
negative regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of protein catabolic process
negative regulation of cyclin-dependent protein serine/threonine kinase activity
negative regulation of innate immune response
negative regulation of smooth muscle cell proliferation
negative regulation of inflammatory response
negative regulation of B cell activation
negative regulation of cell death
cellular response to hydrogen peroxide
negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway
negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway
protein K63-linked deubiquitination
protein K48-linked ubiquitination
protein K48-linked deubiquitination
cellular response to lipopolysaccharide
tolerance induction to lipopolysaccharide
establishment of protein localization to vacuole
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
positive regulation of cellular protein catabolic process
positive regulation of hepatocyte proliferation
negative regulation of CD40 signaling pathway
negative regulation of endothelial cell apoptotic process

Function(s)

protease binding
DNA binding
ubiquitin-protein transferase activity
thiol-dependent ubiquitin-specific protease activity
zinc ion binding
kinase binding
ubiquitin binding
protein self-association