s19741

• Gene Symbol: TOB1
• Gene Name: transducer of ERBB2, 1
• Gene Aliases: APRO5, APRO6, PIG49, TOB, TROB, TROB1
• Chromosome Location: Chr.17: 50862223 - 50867978 on Build GRCh38
• UniGene ID: Hs.703321
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: TOB1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001243877.1	NP_001230806.1	3	500
	NM_001243885.1	NP_001230814.1	2	311
	NM_005749.3	NP_005740.1	2	514
GenBank mRNA	AA675891.1	-	2	225
	AK313904.1	-	3	501
	AY524047.1	-	1	81
	BC031406.1	-	1	78	5194914
	BC070493.1	-	2	502	6470511
	BC098415.1	-	2	506	6480318
	BT019380.1	-	1	71
	BT019381.1	-	1	71
	CR536487.1	-	1	71
	CR541686.1	-	1	71
	D38305.1	-	1	114

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_133317, AF349723.
This siRNA also targets the following transcripts in Mouse: NM_009427, BC082588, AK142667, CF748516.

Gene Ontology Categories:

Process(es)

SMAD protein import into nucleus
negative regulation of cell proliferation
positive regulation of signal transduction
negative regulation of translation
negative regulation of BMP signaling pathway
negative regulation of osteoblast differentiation
negative regulation of nuclear-transcribed mRNA poly(A) tail shortening
positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
negative regulation of nucleic acid-templated transcription

Function(s)

transcription corepressor activity
SH3/SH2 adaptor activity
protein binding
receptor tyrosine kinase binding
SMAD binding