s201590

• Gene Symbol: Lats1
• Gene Name: large tumor suppressor
• Gene Aliases: AW208599
• Chromosome Location: Chr.10: 7681209 - 7716461 on Build GRCm38
• UniGene ID: Mm.34083
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Lats1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_010690.1	NP_034820.1	3	760
GenBank mRNA	AK038612.1	-	3	761
	BC158092.1	-	2	606	9088177
	BC158123.1	-	3	755	9088196

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001134543, XM_008758607, XM_006227614.

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

G2/M transition of mitotic cell cycle
sister chromatid segregation
protein phosphorylation
cell cycle
mitotic nuclear division
hormone-mediated signaling pathway
phosphorylation
keratinocyte differentiation
regulation of actin filament polymerization
positive regulation of peptidyl-serine phosphorylation
cellular protein localization
hippo signaling
regulation of protein complex assembly
negative regulation of cyclin-dependent protein serine/threonine kinase activity
cytoplasmic sequestering of protein
cell division
negative regulation of canonical Wnt signaling pathway

Function(s)

nucleotide binding
magnesium ion binding
protein kinase activity
protein serine/threonine kinase activity
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
protein kinase binding
metal ion binding