s2161

• Gene Symbol: C3
• Gene Name: complement component 3
• Gene Aliases: AHUS5, ARMD9, ASP, C3a, C3b, CPAMD1, HEL-S-62p
• Chromosome Location: Chr.19: 6677835 - 6720682 on Build GRCh38
• UniGene ID: Hs.529053
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: C3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000064.3	NP_000055.2	17, 18	2344
GenBank mRNA	AK304071.1	-	17, 18	2312
	BC150179.1	-	17, 18	2283	40148091
	BC150200.1	-	17, 18	2283	40148812
	EU794602.1	-	17, 18	2283
	K02765.1	-	17, 18	2311
	KC493376.1	-	2, 3	273
	KC493377.1	-	2, 3	274

More Information

Panther Classification:

Molecular Function -

protease inhibitor

Gene Ontology Categories:

Process(es)

positive regulation of type IIa hypersensitivity
positive regulation of protein phosphorylation
positive regulation of activation of membrane attack complex
tolerance induction
proteolysis
fatty acid metabolic process
inflammatory response
immune response
complement activation
complement activation, alternative pathway
complement activation, classical pathway
signal transduction
G-protein coupled receptor signaling pathway
blood coagulation
positive regulation of vascular endothelial growth factor production
positive regulation of glucose transport
regulation of triglyceride biosynthetic process
positive regulation of lipid storage
negative regulation of endopeptidase activity
regulation of complement activation
response to magnesium ion
response to estradiol
response to progesterone
response to estrogen
positive regulation of G-protein coupled receptor protein signaling pathway
positive regulation of angiogenesis
positive regulation of developmental growth
regulation of immune response
response to glucocorticoid
positive regulation of ERK1 and ERK2 cascade
positive regulation of apoptotic cell clearance

Function(s)

serine-type endopeptidase activity
endopeptidase inhibitor activity
receptor binding
protein binding
lipid binding
C5L2 anaphylatoxin chemotactic receptor binding
cofactor binding