s217912

Gene Symbol:

RT1-A1 RT1-A3 RT1-EC2

Gene Name:

RT1 class Ia, locus A1

RT1 class I, locus A3

RT1 class Ib, locus EC2

Gene Aliases:

RT1.A1(N), RT1A-1

RT1-A, RT1.A3

MHCRTA, RATMHCRTA, RT1-A, RT1-Aw2, RT1.Al, RT1.EC2, RT1Aw2, RTS

Chromosome Location:

Chr.20: 5414464 - 5418012 on Build Rnor_6.0

Chromosome Location:

-

Chromosome Location:

-

UniGene ID:

Rn.233151

Rn.116787

Rn.116785

Species:

Rat

Species Specific ID (Flybase ID):

-

-

-

siRNA Details

Gene Symbol: RT1-A1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001008827.1	NP_001008827.1	8	1458
	XM_006256099.2	XP_006256161.1	7	1441
GenBank mRNA	FQ228888.1	-	8	1505
	FQ231496.1	-	6	1112
	KC222922.1	-	7	1363
	U50448.1	-	8	1449

Gene Symbol: RT1-A3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001008830.1	NP_001008830.1	9	1460

Gene Symbol: RT1-EC2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
GenBank mRNA	L26224.1	-	8	1470
	L40363.1	-	9	1451
	M24023.1	-	7	1240
	U38970.1	-	8	1454
	U50447.1	-	10	1449

More Information

Panther Classification:

Molecular Function -

major histocompatibility complex protein

Gene Ontology Categories:

Process(es)

positive regulation of T cell mediated cytotoxicity
antigen processing and presentation of peptide antigen via MHC class I
T cell tolerance induction
positive regulation of tolerance induction to nonself antigen
immune response
negative regulation of natural killer cell mediated cytotoxicity

Function(s)

receptor binding
protein binding
beta-2-microglobulin binding
peptide binding
peptide antigen binding
protein heterodimerization activity