s218005

• Gene Symbol: Nkx2-1
• Gene Name: NK2 homeobox 1
• Gene Aliases: TTF1, Titf1
• Chromosome Location: Chr.6: 77418096 - 77423383 on Build Rnor_6.0
• UniGene ID: Rn.34265
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Nkx2-1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_013093.1	NP_037225.1	2	2035
	XM_006240116.2	XP_006240178.1	3	2316
	XM_006240117.2	XP_006240179.1	3	2389
	XM_006240118.2	XP_006240180.1	3	2900
GenBank mRNA	AB894119.1	-	2	2034
	X53858.1	-	2	2097

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_001079668, NM_003317, U33749, BC006221, U43203.
This siRNA also targets the following transcripts in Mouse: NM_009385, NM_001146198, BC057607, AK136362, BC080868.

Panther Classification:

Molecular Function -

homeodomain transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
neuron migration
regulation of blood volume by renin-angiotensin
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
phospholipid metabolic process
pattern specification process
axon guidance
brain development
endoderm development
circadian rhythm
locomotory behavior
feeding behavior
response to hormone
organ morphogenesis
positive regulation of gene expression
negative regulation of epithelial to mesenchymal transition
telencephalon development
globus pallidus development
hippocampus development
cerebral cortex cell migration
forebrain dorsal/ventral pattern formation
forebrain neuron fate commitment
forebrain neuron differentiation
cerebral cortex GABAergic interneuron differentiation
cerebral cortex neuron differentiation
pituitary gland development
telencephalon cell migration
lung development
negative regulation of cell migration
negative regulation of transforming growth factor beta receptor signaling pathway
thyroid gland development
forebrain development
developmental induction
response to lipopolysaccharide
Leydig cell differentiation
hyperosmotic salinity response
positive regulation of circadian rhythm
response to ethanol
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
development of primary female sexual characteristics
anatomical structure formation involved in morphogenesis
neuron fate commitment
oligodendrocyte differentiation
lung saccule development
epithelial tube branching involved in lung morphogenesis
Clara cell differentiation
Type II pneumocyte differentiation

Function(s)

RNA polymerase II regulatory region sequence-specific DNA binding
core promoter binding
intronic transcription regulatory region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
protein binding
enzyme binding
sequence-specific DNA binding
transcription regulatory region DNA binding