s220349

• Gene Symbol: Siah1
• Gene Name: siah E3 ubiquitin protein ligase 1
• Gene Aliases: SIAH, Siah1a
• Chromosome Location: Chr.19: 21372163 - 21395773 on Build Rnor_6.0
• UniGene ID: Rn.73937
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Siah1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_080905.2	NP_543181.2	2	833
	XM_006255211.2	XP_006255273.1	2	5434
	XM_006255213.2	XP_006255275.1	2	1173
	XM_008772345.1	XP_008770567.1	3	874
GenBank mRNA	AB067814.1	-	2	692
	AF389476.1	-	1	653
	AY681965.1	-	1	653

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_003031, NM_001006610, U63295, BC035562, AB451377, and others.
This siRNA also targets the following transcripts in Mouse: NM_009172, AK219350, Z19579, BC046317.

Panther Classification:

Molecular Function -

ubiquitin-protein ligase, protein modifying enzyme

Gene Ontology Categories:

Process(es)

ubiquitin-dependent protein catabolic process
male meiosis I
multicellular organism development
spermatogenesis
post-embryonic development
cell differentiation
protein catabolic process
protein destabilization
regulation of multicellular organism growth
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
positive regulation of apoptotic process
proteasome-mediated ubiquitin-dependent protein catabolic process
neuron apoptotic process
positive regulation of intrinsic apoptotic signaling pathway

Function(s)

ubiquitin-protein transferase activity
protein binding
protein C-terminus binding
zinc ion binding
ligase activity
protein homodimerization activity
ubiquitin protein ligase activity