s223433

• Gene Symbol: DOCK1
• Gene Name: dedicator of cytokinesis 1
• Gene Aliases: DOCK180, ced5
• Chromosome Location: Chr.10: 126905409 - 127452517 on Build GRCh38
• UniGene ID: Hs.159195
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: DOCK1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001290223.1	NP_001277152.1	43, 44	4531
	NM_001380.4	NP_001371.1	43, 44	4468
	XM_011539422.2	XP_011537724.1	43, 44	4509
	XM_011539424.1	XP_011537726.1	43, 44	4419
	XM_017015813.1	XP_016871302.1	43, 44	4441
	XM_017015816.1	XP_016871305.1	26, 27	2689
GenBank mRNA	BC146857.1	-	43, 44	4421	9056785
	BX648342.1	-	15, 16	2556
	D50857.1	-	43, 44	4382

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001143858, XM_008759987.
This siRNA also targets the following transcripts in Mouse: NM_001033420, AK134905, BC009668, BC006755, BC058998, and others.

Panther Classification:

Molecular Function -

guanyl-nucleotide exchange factor

Gene Ontology Categories:

Process(es)

phagocytosis, engulfment
apoptotic process
cytoskeleton organization
signal transduction
integrin-mediated signaling pathway
small GTPase mediated signal transduction
blood coagulation
positive regulation of epithelial cell migration
cell migration
Fc-gamma receptor signaling pathway involved in phagocytosis
positive regulation of GTPase activity
vascular endothelial growth factor receptor signaling pathway
positive regulation of substrate adhesion-dependent cell spreading

Function(s)

guanyl-nucleotide exchange factor activity
Rho guanyl-nucleotide exchange factor activity
GTPase activator activity
protein binding
SH3 domain binding