s223454

• Gene Symbol: E2F1
• Gene Name: E2F transcription factor 1
• Gene Aliases: E2F-1, RBAP1, RBBP3, RBP3
• Chromosome Location: Chr.20: 33675486 - 33686404 on Build GRCh38
• UniGene ID: Hs.654393
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: E2F1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_005225.2	NP_005216.1	6	996
GenBank mRNA	BC050369.2	-	6	996	6025053
	BC058902.1	-	6	927	6055344
	M96577.1	-	6	991
	S49592.1	-	6	973

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001100778, XM_008762363.
This siRNA also targets the following transcripts in Mouse: NM_007891, NM_001291105, BC052160, AF483514, AK220226, and others.

Panther Classification:

Molecular Function -

RNA metabolism protein, nucleic acid metabolism protein, general transcription factor

Gene Ontology Categories:

Process(es)

DNA damage checkpoint
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription, DNA-templated
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
spermatogenesis
intrinsic apoptotic signaling pathway in response to DNA damage
positive regulation of gene expression
forebrain development
anoikis
negative regulation of DNA binding
negative regulation of fat cell differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of fibroblast proliferation
mRNA stabilization
negative regulation of fat cell proliferation
cellular response to fatty acid
cellular response to hypoxia
cellular response to xenobiotic stimulus
negative regulation of transcription involved in G1/S transition of mitotic cell cycle
intrinsic apoptotic signaling pathway by p53 class mediator
positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
lens fiber cell apoptotic process
cellular response to nerve growth factor stimulus
regulation of G1/S transition of mitotic cell cycle

Function(s)

core promoter binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
transcription factor binding
protein kinase binding
sequence-specific DNA binding