s223945

• Gene Symbol: PDX1
• Gene Name: pancreatic and duodenal homeobox 1
• Gene Aliases: GSF, IDX-1, IPF1, IUF1, MODY4, PAGEN1, PDX-1, STF-1
• Chromosome Location: Chr.13: 27919982 - 27926314 on Build GRCh38
• UniGene ID: Hs.32938
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: PDX1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000209.3	NP_000200.1	2	1287
GenBank mRNA	U30329.1	-	2	1199
	X99894.1	-	2	1278

More Information

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
liver development
type B pancreatic cell differentiation
glucose metabolic process
generation of precursor metabolites and energy
transcription from RNA polymerase II promoter
smoothened signaling pathway
nitric oxide mediated signal transduction
central nervous system development
positive regulation of cell proliferation
negative regulation of cell proliferation
response to wounding
organ morphogenesis
response to iron(II) ion
response to chlorate
organ senescence
positive regulation of cell death
morphogenesis of embryonic epithelium
insulin secretion
exocrine pancreas development
organ regeneration
response to vitamin
response to cytokine
response to nicotine
positive regulation of insulin secretion involved in cellular response to glucose stimulus
response to drug
glucose homeostasis
response to leucine
positive regulation of DNA binding
positive regulation of transcription from RNA polymerase II promoter
digestive tract development
stem cell differentiation
response to glucocorticoid
detection of glucose
transdifferentiation
response to fatty acid
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
negative regulation of type B pancreatic cell apoptotic process

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
core promoter sequence-specific DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
transcription factor binding
protein complex binding
protein heterodimerization activity