s223963

Gene Symbol:

KCNE1 KCNE1B

Gene Name:

potassium voltage-gated channel subfamily E regulatory subunit 1

potassium voltage-gated channel subfamily E regulatory subunit 1B

Gene Aliases:

ISK, JLNS, JLNS2, LQT2/5, LQT5, MinK

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Chromosome Location:

Chr.21: 34446688 - 34512275 on Build GRCh38

Chromosome Location:

Chr.21: 7816677 - 7829632 on Build GRCh38

UniGene ID:

Hs.121495

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Species:

Human

Species Specific ID (Flybase ID):

-

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siRNA Details

Gene Symbol: KCNE1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000219.5	NP_000210.2	4	1655
	NM_001127668.3	NP_001121140.1	3	1267
	NM_001127669.3	NP_001121141.1	3	1239
	NM_001127670.3	NP_001121142.1	2	1504
	NM_001270402.2	NP_001257331.1	3	1430
	NM_001270403.2	NP_001257332.1	3	1378
	NM_001270404.2	NP_001257333.1	2	1319
	NM_001270405.2	NP_001257334.1	3	1231
	XM_017028342.1	XP_016883831.1	2	3007
GenBank mRNA	AK304336.1	-	3	1323
	AK311384.1	-	4	842

Gene Symbol: KCNE1B
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	XM_006723946.2	XP_006724009.1	2	1460
	XM_006723949.2	XP_006724012.1	3	1307

More Information

Panther Classification:

Molecular Function -

voltage-gated ion channel

Gene Ontology Categories:

Process(es)

protein N-linked glycosylation
protein O-linked glycosylation
sensory perception of sound
regulation of ventricular cardiac muscle cell membrane repolarization
cardiac conduction
cellular response to cAMP
potassium ion export
potassium ion transmembrane transport
cardiac muscle cell action potential involved in contraction
ventricular cardiac muscle cell action potential
membrane repolarization
membrane repolarization during action potential
membrane repolarization during cardiac muscle cell action potential
regulation of heart rate by cardiac conduction
negative regulation of protein targeting to membrane
membrane repolarization during ventricular cardiac muscle cell action potential
regulation of potassium ion transmembrane transport
positive regulation of potassium ion transmembrane transport
regulation of delayed rectifier potassium channel activity
negative regulation of delayed rectifier potassium channel activity

Function(s)

voltage-gated potassium channel activity
delayed rectifier potassium channel activity
protein binding
potassium channel regulator activity
telethonin binding
voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization
voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization