s223986

• Gene Symbol: HES5
• Gene Name: hes family bHLH transcription factor 5
• Gene Aliases: bHLHb38
• Chromosome Location: Chr.1: 2528745 - 2530554 on Build GRCh38
• UniGene ID: Hs.57971
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: HES5
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001010926.3	NP_001010926.1	3	1218
	XM_005244751.4	XP_005244808.1	2	1623
GenBank mRNA	BC087840.1	-	1	1413	6204648
	BX104111.1	-	1	414
	DQ272660.1	-	3	1218

More Information

Panther Classification:

Molecular Function -

basic helix-loop-helix transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
chondrocyte differentiation
transcription, DNA-templated
protein complex assembly
cell adhesion
Notch signaling pathway
smoothened signaling pathway
brain development
positive regulation of cell proliferation
oligodendrocyte development
telencephalon development
glial cell fate commitment
forebrain radial glial cell differentiation
neural tube development
central nervous system myelination
positive regulation of BMP signaling pathway
regulation of myelination
auditory receptor cell differentiation
positive regulation of tyrosine phosphorylation of Stat3 protein
auditory receptor cell fate determination
camera-type eye development
regulation of cell differentiation
regulation of auditory receptor cell differentiation
negative regulation of neuron differentiation
positive regulation of Notch signaling pathway
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of JAK-STAT cascade
cell maturation
positive regulation of smooth muscle cell proliferation
astrocyte differentiation
negative regulation of astrocyte differentiation
negative regulation of oligodendrocyte differentiation
regulation of epithelial cell proliferation
regulation of neurogenesis
cartilage development
inner ear receptor stereocilium organization
comma-shaped body morphogenesis
S-shaped body morphogenesis
specification of loop of Henle identity
metanephric nephron tubule morphogenesis
establishment of epithelial cell polarity
neuronal stem cell population maintenance
negative regulation of stem cell differentiation
negative regulation of pro-B cell differentiation
negative regulation of forebrain neuron differentiation
negative regulation of inner ear receptor cell differentiation

Function(s)

transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
chromatin binding
double-stranded DNA binding
transcription factor binding
protein dimerization activity