s224476

• Gene Symbol: MKL1
• Gene Name: megakaryoblastic leukemia (translocation) 1
• Gene Aliases: BSAC, MAL, MRTF-A
• Chromosome Location: Chr.22: 40410281 - 40636719 on Build GRCh38
• UniGene ID: Hs.654688
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: MKL1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001282660.1	NP_001269589.1	10, 11	2435
	NM_001282661.1	NP_001269590.1	12, 13	2697
	NM_001282662.1	NP_001269591.1	13, 14	2847
	NM_001318139.1	NP_001305068.1	11, 12	2572
	NM_020831.4	NP_065882.1	13, 14	2847
	XM_005261692.1	XP_005261749.1	12, 13	2652
	XM_005261694.1	XP_005261751.1	12, 13	2742
	XM_011530283.1	XP_011528585.1	14, 15	2955
	XM_011530285.1	XP_011528587.1	14, 15	2866
	XM_011530287.1	XP_011528589.1	6, 7	1834
	XM_017028888.1	XP_016884377.1	13, 14	2930
	XM_017028889.1	XP_016884378.1	9, 10	3930
GenBank mRNA	AB037859.2	-	13, 14	2819
	AF368061.1	-	13, 14	2772
	AJ297257.1	-	10, 11	2429
	AJ297258.1	-	13, 14	2829
	AL713710.1	-	5, 6	1642
	BC115039.1	-	13, 14	2813	5551767
	BC139730.1	-	11, 12	1600
	CR456522.1	-	10, 11	2246
	HG764171.1	-	11, 12	2572

More Information

Panther Classification:

Molecular Function -

DNA-binding transcription factor

Gene Ontology Categories:

Process(es)

transcription, DNA-templated
positive regulation of transcription via serum response element binding
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of transcription from RNA polymerase II promoter
smooth muscle cell differentiation
negative regulation of apoptotic signaling pathway

Function(s)

transcription regulatory region sequence-specific DNA binding
RNA polymerase II transcription coactivator activity
transcription factor activity, sequence-specific DNA binding
transcription coactivator activity
actin binding
actin monomer binding
protein binding
leucine zipper domain binding