s224482

• Gene Symbol: PTN
• Gene Name: pleiotrophin
• Gene Aliases: HARP, HB-GAM, HBBM, HBGF-8, HBGF8, HBNF, HBNF-1, NEGF1, OSF-1
• Chromosome Location: Chr.7: 137227341 - 137343865 on Build GRCh38
• UniGene ID: Hs.371249
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: PTN
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001321386.1	NP_001308315.1	3	373
	NM_001321387.1	NP_001308316.1	3	675
	NM_002825.5	NP_002816.1	3	610
	XM_017012473.1	XP_016867962.1	3	493
GenBank mRNA	AK290488.1	-	3	439
	AK313424.1	-	3	513
	BC005916.1	-	3	598	4248708
	BI462078.1	-	3	382
	BT019692.1	-	2	247
	BX420480.2	-	3	674
	BX441769.2	-	3	378
	CN413530.1	-	3	359
	CR450338.1	-	2	247
	D90226.1	-	3	371
	M57399.1	-	3	642
	X52946.1	-	3	498

More Information

Panther Classification:

Molecular Function -

growth factor

Gene Ontology Categories:

Process(es)

liver development
transmembrane receptor protein tyrosine phosphatase signaling pathway
nervous system development
heart development
learning
positive regulation of cell proliferation
regulation of cell shape
positive regulation of cell-substrate adhesion
positive regulation of neuron projection development
response to activity
negative regulation of angiogenesis
spinal cord development
cerebellum development
thalamus development
bone mineralization
lung development
negative regulation of cell migration
response to estradiol
response to progesterone
cellular response to UV
cellular response to platelet-derived growth factor stimulus
response to drug
positive regulation of apoptotic process
negative regulation of catalytic activity
estrous cycle
endothelial cell differentiation
negative regulation of membrane potential
negative regulation of epithelial cell proliferation
positive regulation of cell division
retinal rod cell differentiation
negative regulation of glial cell proliferation
long-term synaptic potentiation
cellular response to vitamin D
cellular response to hypoxia
negative regulation of mesenchymal cell proliferation
response to kainic acid
rod bipolar cell differentiation
response to ciliary neurotrophic factor
positive regulation of skeletal muscle acetylcholine-gated channel clustering
negative regulation of neuromuscular junction development
response to nerve growth factor
positive regulation of hepatocyte proliferation

Function(s)

protein phosphatase inhibitor activity
growth factor activity
heparin binding
chondroitin sulfate proteoglycan binding
chondroitin sulfate binding
vascular endothelial growth factor binding
heparan sulfate binding