s224623

• Gene Symbol: SMURF2
• Gene Name: SMAD specific E3 ubiquitin protein ligase 2
• Gene Aliases: -
• Chromosome Location: Chr.17: 64542282 - 64662268 on Build GRCh38
• UniGene ID: Hs.515011
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: SMURF2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_022739.3	NP_073576.1	9, 10	1254
	XM_005257585.3	XP_005257642.1	8, 9	854
	XM_011525128.1	XP_011523430.1	9, 10	872
GenBank mRNA	AF301463.1	-	9, 10	874
	AF310676.1	-	9, 10	866
	AY014180.1	-	9, 10	1054
	BC093876.1	-	9, 10	936	7939721
	BC111945.1	-	9, 10	938	8327413
	CR936721.1	-	10, 11	989

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001107061, XM_008768365.
This siRNA also targets the following transcripts in Mouse: NM_025481, BC138786, AY685230, AK012060, BC138788.

Panther Classification:

Molecular Function -

ubiquitin-protein ligase

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
protein polyubiquitination
ubiquitin-dependent protein catabolic process
regulation of transforming growth factor beta receptor signaling pathway
BMP signaling pathway
negative regulation of transforming growth factor beta receptor signaling pathway
ubiquitin-dependent SMAD protein catabolic process
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
negative regulation of transcription, DNA-templated
Wnt signaling pathway, planar cell polarity pathway
positive regulation of canonical Wnt signaling pathway
positive regulation of trophoblast cell migration

Function(s)

ubiquitin-protein transferase activity
transforming growth factor beta receptor binding
protein binding
ligase activity
identical protein binding
SMAD binding
ubiquitin protein ligase activity