s226362

• Gene Symbol: GEN1
• Gene Name: GEN1, Holliday junction 5' flap endonuclease
• Gene Aliases: Gen
• Chromosome Location: Chr.2: 17753687 - 17785920 on Build GRCh38
• UniGene ID: Hs.467793
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: GEN1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001130009.2	NP_001123481.2	11	1350
	NM_182625.4	NP_872431.4	11	1274
	XM_005262613.4	XP_005262670.1	11	1360
	XM_006712005.3	XP_006712068.1	11	1257
	XM_011532820.2	XP_011531122.1	11	1277
	XM_011532821.2	XP_011531123.1	11	1367
	XM_011532822.2	XP_011531124.1	11	1247
GenBank mRNA	AK098188.1	-	4	300
	AK131387.1	-	11	1222
	BC117204.1	-	10	1172	40125755
	BC117206.1	-	10	1172	40125757
	CR936783.1	-	11	1360

More Information

Panther Classification:

Molecular Function -

exodeoxyribonuclease

Gene Ontology Categories:

Process(es)

double-strand break repair via homologous recombination
regulation of centrosome duplication
resolution of recombination intermediates
resolution of mitotic recombination intermediates
positive regulation of mitotic cell cycle spindle assembly checkpoint
nucleic acid phosphodiester bond hydrolysis

Function(s)

DNA binding
endodeoxyribonuclease activity
crossover junction endodeoxyribonuclease activity
metal ion binding