s226363

• Gene Symbol: GEN1
• Gene Name: GEN1, Holliday junction 5' flap endonuclease
• Gene Aliases: Gen
• Chromosome Location: Chr.2: 17753687 - 17785920 on Build GRCh38
• UniGene ID: Hs.467793
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: GEN1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001130009.2	NP_001123481.2	12	1421
	NM_182625.4	NP_872431.4	12	1345
	XM_005262613.4	XP_005262670.1	12	1431
	XM_006712005.3	XP_006712068.1	12	1328
	XM_011532820.2	XP_011531122.1	12	1348
	XM_011532821.2	XP_011531123.1	12	1438
	XM_011532822.2	XP_011531124.1	12	1318
GenBank mRNA	AK098188.1	-	5	371
	AK131387.1	-	12	1293
	BC117204.1	-	11	1243	40125755
	BC117206.1	-	11	1243	40125757
	CR936783.1	-	12	1431

More Information

Panther Classification:

Molecular Function -

exodeoxyribonuclease

Gene Ontology Categories:

Process(es)

double-strand break repair via homologous recombination
regulation of centrosome duplication
resolution of recombination intermediates
resolution of mitotic recombination intermediates
positive regulation of mitotic cell cycle spindle assembly checkpoint
nucleic acid phosphodiester bond hydrolysis

Function(s)

DNA binding
endodeoxyribonuclease activity
crossover junction endodeoxyribonuclease activity
metal ion binding