s229258

• Gene Symbol: SCX
• Gene Name: scleraxis bHLH transcription factor
• Gene Aliases: SCXA, SCXB, bHLHa48
• Chromosome Location: Chr.8: 144265060 - 144268483 on Build GRCh38
• UniGene ID: Hs.553250
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: SCX
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001080514.2	NP_001073983.1	1	325
	XM_006716616.2	XP_006716679.1	2	1414
GenBank mRNA	CD672767.1	-	1	325

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001130508, BC169036.
This siRNA also targets the following transcripts in Mouse: NM_198885, S78079, AK013456, BC062161, AB221642.

Panther Classification:

Molecular Function -

basic helix-loop-helix transcription factor

Gene Ontology Categories:

Process(es)

mesoderm formation
tissue homeostasis
endochondral ossification
chondrocyte differentiation
heart valve morphogenesis
heart valve formation
transcription, DNA-templated
transcription from RNA polymerase II promoter
positive regulation of cell proliferation
positive regulation of gene expression
cell differentiation
collagen fibril organization
BMP signaling pathway
positive regulation of collagen biosynthetic process
skeletal muscle cell differentiation
tendon development
tendon cell differentiation
tendon formation
deltoid tuberosity development
negative regulation of apoptotic process
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
embryonic skeletal system development
Sertoli cell differentiation
face morphogenesis
regulation of cartilage development
positive regulation of cartilage development
sclerotome development
cellular response to mechanical stimulus
cellular response to transforming growth factor beta stimulus
positive regulation of gastrulation

Function(s)

RNA polymerase II distal enhancer sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding
DNA binding
bHLH transcription factor binding
sequence-specific DNA binding
protein heterodimerization activity
E-box binding