s23074

• Gene Symbol: TAB2
• Gene Name: TGF-beta activated kinase 1/MAP3K7 binding protein 2
• Gene Aliases: CHTD2, MAP3K7IP2, TAB-2
• Chromosome Location: Chr.6: 149217924 - 149411613 on Build GRCh38
• UniGene ID: Hs.269775
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: TAB2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001292034.2	NP_001278963.1	2	219
	NM_015093.5	NP_055908.1	4	462
	XM_011535633.2	XP_011533935.1	3	901
	XM_017010591.1	XP_016866080.1	3	432
	XM_017010592.1	XP_016866081.1	3	969
GenBank mRNA	AB018276.2	-	2	216
	AF241230.1	-	1	121
	AK307650.1	-	4	449
	AK315038.1	-	4	456
	AL117407.1	-	2	151
	BC035910.2	-	2	177	5492359
	CR457387.1	-	1	41

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001012062, XM_006227618, XM_008758608, XM_006227617, XM_006227620, and others.
This siRNA also targets the following transcripts in Mouse: NM_138667, AK086230, AK147830, AY093701, BC004813, and others.

Gene Ontology Categories:

Process(es)

activation of MAPK activity
stimulatory C-type lectin receptor signaling pathway
MyD88-dependent toll-like receptor signaling pathway
I-kappaB kinase/NF-kappaB signaling
JNK cascade
heart development
negative regulation of autophagy
Fc-epsilon receptor signaling pathway
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of protein kinase activity
T cell receptor signaling pathway
positive regulation of NF-kappaB transcription factor activity
nucleotide-binding oligomerization domain containing signaling pathway

Function(s)

protein binding
zinc ion binding
K63-linked polyubiquitin binding