s232352

• Gene Symbol: Ccl5
• Gene Name: chemokine (C-C motif) ligand 5
• Gene Aliases: MuRantes, RANTES, SISd, Scya5, TCP228
• Chromosome Location: Chr.11: 83525778 - 83530518 on Build GRCm38
• UniGene ID: Mm.284248
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Ccl5
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_013653.3	NP_038681.2	3	502
GenBank mRNA	AK158074.1	-	2	3589
	BC033508.1	-	3	485	4925413
	BE333205.1	-	1	271
	M77747.1	-	3	491

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_031116.

Panther Classification:

Molecular Function -

cytokine, intercellular signal molecule

Gene Ontology Categories:

Process(es)

MAPK cascade
positive regulation of defense response to virus by host
calcium ion transport
cellular calcium ion homeostasis
exocytosis
chemotaxis
inflammatory response
immune response
leukocyte cell-cell adhesion
G-protein coupled receptor signaling pathway
cell-cell signaling
response to toxic substance
positive regulation of gene expression
positive regulation of macrophage chemotaxis
positive regulation of T cell chemotaxis
positive regulation of phosphatidylinositol 3-kinase signaling
positive regulation of smooth muscle cell migration
positive regulation of cell migration
pseudopodium assembly
positive regulation of cellular biosynthetic process
activation of phospholipase D activity
positive regulation of fever generation
lipopolysaccharide-mediated signaling pathway
positive regulation of cell-cell adhesion mediated by integrin
response to cytokine
positive regulation of homotypic cell-cell adhesion
response to interferon-gamma
response to tumor necrosis factor
T-helper 1 cell diapedesis
positive regulation of T cell proliferation
neutrophil activation
positive regulation of phosphorylation
positive regulation of tyrosine phosphorylation of STAT protein
protein kinase B signaling
cellular protein complex assembly
negative regulation by host of viral transcription
negative regulation of viral genome replication
positive regulation of neuron differentiation
positive regulation of osteoclast differentiation
negative regulation of G-protein coupled receptor protein signaling pathway
positive regulation of angiogenesis
positive regulation of cell adhesion
eosinophil chemotaxis
lymphocyte chemotaxis
positive regulation of smooth muscle cell proliferation
positive regulation of epithelial cell proliferation
regulation of insulin secretion
regulation of T cell activation
positive chemotaxis
protein tetramerization
positive regulation of calcium ion transport
negative regulation of cell death
positive regulation of mast cell chemotaxis
positive regulation of protein tyrosine kinase activity
chemokine-mediated signaling pathway
negative regulation of chemokine-mediated signaling pathway
negative regulation of T cell apoptotic process
positive regulation of T cell apoptotic process
cellular response to organic cyclic compound
positive regulation of monocyte chemotaxis
extracellular negative regulation of signal transduction
regulation of neuron death
negative regulation of neuron death
negative regulation of macrophage apoptotic process
negative regulation of receptor activity
positive regulation of chemokine (C-X-C motif) ligand 2 production
positive regulation of T cell migration
positive regulation of natural killer cell chemotaxis

Function(s)

phosphatidylinositol phospholipase C activity
protein kinase activity
cytokine activity
chemokine activity
heparin binding
phospholipase activator activity
receptor signaling protein tyrosine kinase activator activity
CCR1 chemokine receptor binding
CCR5 chemokine receptor binding
chemoattractant activity
chemokine receptor binding
protein homodimerization activity
protein self-association
chemokine receptor antagonist activity