s2340 Validated

• Gene Symbol: CALM1
• Gene Name: calmodulin 1
• Gene Aliases: CALML2, CAMI, CPVT4, DD132, LQT14, PHKD, caM
• Chromosome Location: Chr.14: 90396983 - 90408275 on Build GRCh38
• UniGene ID: Hs.282410
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: CALM1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_006888.4	NP_008819.1	4	519
	XM_006720258.3	XP_006720321.1	4	1148
GenBank mRNA	AK289937.1	-	5	466
	AU122722.1	-	4	473
	AY189287.1	-	3	2400
	BC000454.2	-	4	453	2821489
	BC007965.2	-	4	495	4308380
	BC008597.1	-	4	453	3452971
	BC011834.2	-	4	473	3942245
	BC047523.1	-	4	473
	BT006818.1	-	3	271
	M27319.1	-	4	358

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_031969, FQ232999, AF178845, FQ226971, FQ211760, and others.

Matching Taqman Gene Expression Assay:

Hs00237233_m1

Panther Classification:

Molecular Function -

calmodulin-related

Gene Ontology Categories:

Process(es)

G2/M transition of mitotic cell cycle
MAPK cascade
response to amphetamine
regulation of heart rate
platelet degranulation
detection of calcium ion
glycogen catabolic process
muscle contraction
G-protein coupled receptor signaling pathway
activation of adenylate cyclase activity
Wnt signaling pathway, calcium modulating pathway
positive regulation of peptidyl-threonine phosphorylation
negative regulation of peptidyl-threonine phosphorylation
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
substantia nigra development
regulation of rhodopsin mediated signaling pathway
positive regulation of cyclic nucleotide metabolic process
positive regulation of protein autophosphorylation
regulation of cytokinesis
positive regulation of phosphoprotein phosphatase activity
ion transmembrane transport
positive regulation of protein dephosphorylation
Fc-epsilon receptor signaling pathway
positive regulation of DNA binding
positive regulation of GTPase activity
inositol phosphate metabolic process
regulation of nitric-oxide synthase activity
positive regulation of nitric-oxide synthase activity
positive regulation of cyclic-nucleotide phosphodiesterase activity
response to corticosterone
response to calcium ion
regulation of cardiac muscle contraction
negative regulation of ryanodine-sensitive calcium-release channel activity
positive regulation of ryanodine-sensitive calcium-release channel activity
positive regulation of protein serine/threonine kinase activity
regulation of high voltage-gated calcium channel activity
regulation of cell communication by electrical coupling involved in cardiac conduction

Function(s)

Ras guanyl-nucleotide exchange factor activity
calcium ion binding
protein binding
adenylate cyclase binding
inositol-1,4,5-trisphosphate 3-kinase activity
ligand-gated ion channel activity
protein kinase binding
protein domain specific binding
nitric-oxide synthase regulator activity
titin binding
type 3 metabotropic glutamate receptor binding
thioesterase binding
N-terminal myristoylation domain binding
phospholipase binding
protein serine/threonine kinase activator activity
phosphatidylinositol 3-kinase binding
ion channel binding
calcium-dependent protein binding
nitric-oxide synthase binding
protein phosphatase activator activity