s234450

Gene Symbol:

Insl3 Jak3

Gene Name:

insulin-like 3

Janus kinase 3

Gene Aliases:

Rlf, Rlnl

fae, wil

Chromosome Location:

Chr.8: 71689252 - 71690577 on Build GRCm38

Chromosome Location:

Chr.8: 71676383 - 71690577 on Build GRCm38

UniGene ID:

Mm.476857

Mm.249645

Species:

Mouse

Species Specific ID (Flybase ID):

-

-

siRNA Details

Gene Symbol: Insl3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_013564.7	NP_038592.3	2	468
GenBank mRNA	AK132857.1	-	2	469
	BC049540.1	-	2	468	6773462
	S82815.1	-	2	467

Gene Symbol: Jak3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_010589.6	NP_034719.2	25	3815
GenBank mRNA	AK038268.1	-	24	3626
	AK088365.1	-	25	3664
	BC105577.1	-	24	3618	3968386
	L32955.1	-	24	3603

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_053680, XM_006252820, AF139918, BC098653.

Gene Ontology Categories:

Process(es)

oocyte maturation
in utero embryonic development
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
positive regulation of cell proliferation
negative regulation of cell proliferation
male gonad development
positive regulation of epithelial cell migration
positive regulation of cAMP biosynthetic process
negative regulation of apoptotic process
positive regulation of wound healing
immune system process
negative regulation of dendritic cell cytokine production
protein phosphorylation
enzyme linked receptor protein signaling pathway
transmembrane receptor protein tyrosine kinase signaling pathway
positive regulation of cytosolic calcium ion concentration
tyrosine phosphorylation of STAT protein
phosphorylation
cell migration
peptidyl-tyrosine phosphorylation
cytokine-mediated signaling pathway
B cell differentiation
erythrocyte differentiation
negative regulation of interleukin-10 production
negative regulation of interleukin-12 production
intracellular signal transduction
interleukin-4-mediated signaling pathway
peptidyl-tyrosine autophosphorylation
positive regulation of T cell proliferation
positive regulation of activated T cell proliferation
tyrosine phosphorylation of Stat5 protein
T cell homeostasis
innate immune response
negative regulation of FasL biosynthetic process
negative regulation of T-helper 1 cell differentiation
positive regulation of transcription from RNA polymerase II promoter
protein autophosphorylation
lymph node development
positive regulation of immune response
negative regulation of T cell activation
positive regulation of calcium ion transport
regulation of T cell apoptotic process
negative regulation of thymocyte apoptotic process
response to interleukin-2
response to interleukin-4
response to interleukin-15
response to interleukin-9
positive regulation of dendritic cell apoptotic process
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand

Function(s)

G-protein coupled receptor binding
protease binding
hormone activity
nucleotide binding
protein kinase activity
protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
protein binding
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
protein phosphatase binding
hormone receptor binding