s234483

• Gene Symbol: Gnas
• Gene Name: GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus
• Gene Aliases: 5530400H20Rik, A930027G11Rik, C130027O20Rik, GPSA, GSP, Galphas, Gnas1, Gnasxl, Gsa, Nesp, Nespl, Oed-Sml, Oedsml, P1, P2, P3, PHP1A, PHP1B, POH
• Chromosome Location: Chr.2: 174283444 - 174346744 on Build GRCm38
• UniGene ID: Mm.125770
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Gnas
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001077507.1	NP_001070975.1	11	3384
	NM_001077510.2	NP_001070978.1	11	1371
	NM_010309.3	NP_034439.2	12	3426
	NM_022000.2	NP_068840.2	13	2131
	NM_201616.1	NP_963910.1	12	1413
	NM_201618.1	NP_963912.1	12	3426
GenBank mRNA	AF107848.1	-	13	2129
	AF116268.1	-	11	2313
	AK078037.1	-	12	1423
	AK132636.1	-	12	1514
	AK147051.1	-	11	1369
	AK159563.1	-	12	1414
	AK168996.1	-	12	1384
	AY519501.1	-	12	3426
	AY519502.1	-	12	3426
	AY519504.1	-	13	3521
	AY682719.1	-	13	1119
	BC013824.1	-	12	1225
	BC013840.1	-	12	1225
	BC018408.1	-	3	339
	BC034446.1	-	11	1465
	BC038067.1	-	13	1425
	BC048834.1	-	9	930
	BC061496.1	-	11	1355
	BC062654.1	-	13	3568
	BC080816.1	-	12	1402
	BC092055.1	-	12	1217
	BC106133.1	-	11	1177
	M13964.1	-	11	1171
	Y00703.1	-	12	1225

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001159653, NM_001024823, NM_019132, NM_021845, AF105254, and others.

Panther Classification:

Molecular Function -

heterotrimeric G-protein

Gene Ontology Categories:

Process(es)

skeletal system development
tissue homeostasis
positive regulation of protein phosphorylation
endochondral ossification
energy reserve metabolic process
DNA methylation
regulation of transcription from RNA polymerase II promoter
signal transduction
G-protein coupled receptor signaling pathway
adenylate cyclase-activating G-protein coupled receptor signaling pathway
adenylate cyclase-activating dopamine receptor signaling pathway
sensory perception of chemical stimulus
post-embryonic development
regulation of signal transduction
positive regulation of sodium ion transport
positive regulation of cAMP biosynthetic process
embryonic hindlimb morphogenesis
multicellular organism growth
negative regulation of renal sodium excretion
negative regulation of multicellular organism growth
post-embryonic body morphogenesis
response to drug
positive regulation of GTPase activity
skin development
positive regulation of cAMP-mediated signaling
positive regulation of osteoblast differentiation
positive regulation of osteoclast differentiation
negative regulation of blood pressure
developmental growth
embryonic cranial skeleton morphogenesis
cognition
cartilage development
calcium ion homeostasis
bone development
hair follicle placode formation
platelet aggregation
response to parathyroid hormone
cellular response to prostaglandin E stimulus
genetic imprinting
cellular response to catecholamine stimulus
adenylate cyclase-activating adrenergic receptor signaling pathway

Function(s)

nucleotide binding
G-protein alpha-subunit binding
GTPase activity
signal transducer activity
insulin-like growth factor receptor binding
protein binding
GTP binding
guanyl nucleotide binding
protein domain specific binding
G-protein beta-subunit binding
G-protein beta/gamma-subunit complex binding
beta-2 adrenergic receptor binding
D1 dopamine receptor binding
mu-type opioid receptor binding
ionotropic glutamate receptor binding
alpha-tubulin binding
metal ion binding
corticotropin-releasing hormone receptor 1 binding