s236912

Gene Symbol:

RT1-CE12 RT1-A1 RT1-A2 RT1-A3 RT1-CE1 RT1-CE10 RT1-CE14 RT1-CE2 RT1-CE3 RT1-CE4 RT1-EC2 Rt1.aa

Gene Name:

RT1 class I, locus CE12

RT1 class Ia, locus A1

RT1 class Ia, locus A2

RT1 class I, locus A3

RT1 class I, locus1

RT1 class I, locus CE10

RT1 class I, locus CE14

RT1 class I, locus CE2

RT1 class I, locus CE3

RT1 class I, locus CE4

RT1 class Ib, locus EC2

MHC class I RT1.Aa alpha-chain

Gene Aliases:

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RT1.A1(N), RT1A-1

RT1.A2(N), RT1A-2

RT1-A, RT1.A3

RT1-C/E1

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-

RT1-C/E2

RT1-C/E3

RT1-C/E4

MHCRTA, RATMHCRTA, RT1-A, RT1-Aw2, RT1.Al, RT1.EC2, RT1Aw2, RTS

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Chromosome Location:

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Chromosome Location:

Chr.20: 5414464 - 5418012 on Build Rnor_6.0

Chromosome Location:

Chr.20: 5375011 - 5378536 on Build Rnor_6.0

Chromosome Location:

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Chromosome Location:

Chr.20: 4638235 - 4792390 on Build Rnor_6.0

Chromosome Location:

Chr.20: 154072 - 157679 on Build Rnor_6.0

Chromosome Location:

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Chromosome Location:

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Chromosome Location:

Chr.20: 4931965 - 4935372 on Build Rnor_6.0

Chromosome Location:

Chr.20: 4918523 - 4921339 on Build Rnor_6.0

Chromosome Location:

-

Chromosome Location:

-

UniGene ID:

Rn.128939

Rn.233151

Rn.116787

Rn.116787

Rn.203332

Rn.219012

Rn.234142

Rn.120283

Rn.40130

Rn.215620

Rn.116785

Rn.116787

Species:

Rat

Species Specific ID (Flybase ID):

-

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siRNA Details

Gene Symbol: RT1-CE12
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001008835.1	NP_001008835.1		448

Gene Symbol: RT1-A1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001008827.1	NP_001008827.1	3	448
	XM_006256099.2	XP_006256161.1	3	479
GenBank mRNA	FQ228888.1	-	3	495
	FQ231496.1	-	3	468
	KC222922.1	-	2	353
	U50448.1	-	3	439
	X90375.1	-	2	376

Gene Symbol: RT1-A2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001008829.1	NP_001008829.1	3	442
GenBank mRNA	BC088465.1	-	3	458	7127909
	FQ233418.1	-	3	468
	X90376.1	-	2	376

Gene Symbol: RT1-A3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001008830.1	NP_001008830.1	4	439
GenBank mRNA	U38971.1	-	4	439

Gene Symbol: RT1-CE1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001008832.2	NP_001008832.1	3	448
	XM_008772726.1	XP_008770948.1	3	579
	XM_008772727.1	XP_008770949.1	3	582
GenBank mRNA	AJ005022.1	-	2	376

Gene Symbol: RT1-CE10
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001008833.1	NP_001008833.1	3	448
	XM_006255847.2	XP_006255909.1	3	453
GenBank mRNA	BC083874.1	-	2	632
	BC098952.1	-	3	451	7366301

Gene Symbol: RT1-CE14
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001008837.1	NP_001008837.1	3	448
	NM_001033985.1	NP_001029157.1	2	452
GenBank mRNA	BC083799.1	-	2	452	7108728

Gene Symbol: RT1-CE2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001008840.1	NP_001008840.1	3	439

Gene Symbol: RT1-CE3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001008841.2	NP_001008841.1	3	448

Gene Symbol: RT1-CE4
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001008842.1	NP_001008842.1	3	448

Gene Symbol: RT1-EC2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_012645.1	NP_036777.1	3	457
GenBank mRNA	AF400159.1	-	3	457
	AJ004887.1	-	2	376
	AJ004888.1	-	2	376
	AJ005024.1	-	2	376
	AJ005025.1	-	2	376
	AJ249698.1	-	3	376
	AJ249699.1	-	2	376
	AJ249700.1	-	2, 3	376
	AJ249701.1	-	3	376
	AJ249702.1	-	3	376
	AJ249703.1	-	3	382
	AJ249704.1	-	2	376
	AJ249705.1	-	2	376
	AJ306619.1	-	3	457
	BC061817.1	-	4	458	5598840
	L26224.1	-	3	457
	L40363.1	-	4	436
	L40365.1	-	3	457
	M24023.1	-	2	226
	M25319.1	-	2	436
	M31018.1	-	4	457
	M31038.1	-	3	457
	U38970.1	-	3	439
	U38972.1	-	4	439
	X82106.1	-	2	376
	X90370.1	-	2	376
	X90371.1	-	3	376
	X90372.1	-	2	376
	X90373.1	-	3	376
	X90374.1	-	2	376
	X99767.1	-	2	376
	Y08532.1	-	3	376
	Y13579.1	-	2	376

Gene Symbol: Rt1.aa
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001134701.1	NP_001128173.1	4	453
GenBank mRNA	BC166751.1	-	4	453	5621043
	Y14014.1	-	3	376

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: D87665.
This siRNA also targets the following transcripts in Mouse: NM_207648, NM_001025208, NM_001143689, NM_010394, NM_010380, and others.

Panther Classification:

Molecular Function -

major histocompatibility complex protein

Gene Ontology Categories:

Process(es)

positive regulation of T cell mediated cytotoxicity
antigen processing and presentation of peptide antigen via MHC class I
T cell tolerance induction
positive regulation of tolerance induction to nonself antigen
immune response
negative regulation of natural killer cell mediated cytotoxicity
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent

Function(s)

receptor binding
protein binding
beta-2-microglobulin binding
peptide binding
peptide antigen binding
protein heterodimerization activity