s2410 Validated

• Gene Symbol: CASP2
• Gene Name: caspase 2
• Gene Aliases: CASP-2, ICH1, NEDD-2, NEDD2, PPP1R57
• Chromosome Location: Chr.7: 143288215 - 143307696 on Build GRCh38
• UniGene ID: Hs.368982
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: CASP2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001224.4	NP_001215.1	2	151
	NM_032982.3	NP_116764.2	2	397
	NM_032983.3	NP_116765.2	2	397
GenBank mRNA	AF314174.1	-	2	105
	AF314175.1	-	1	63
	AK291274.1	-	2	189
	AK303391.1	-	2	169
	BC002427.2	-	2	169	3346279
	BG397039.1	-	2	228
	BT007240.1	-	2	105
	CB988674.1	-	2	330
	CR541748.1	-	1	63
	DA505883.1	-	2	398
	DB455837.1	-	2	362
	DB455840.1	-	2	362
	KU177957.1	-	2	156
	KU177958.1	-	2	156
	U13021.1	-	2	118
	U13022.1	-	2	151

More Information

Matching Taqman Gene Expression Assay:

Hs00154242_m1

Panther Classification:

Molecular Function -

protease

Gene Ontology Categories:

Process(es)

luteolysis
neural retina development
apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
brain development
aging
intrinsic apoptotic signaling pathway in response to DNA damage
protein processing
ectopic germ cell programmed cell death
regulation of apoptotic process
positive regulation of apoptotic process
positive regulation of neuron apoptotic process
cellular response to mechanical stimulus
apoptotic signaling pathway
extrinsic apoptotic signaling pathway in absence of ligand
execution phase of apoptosis
positive regulation of apoptotic signaling pathway

Function(s)

cysteine-type endopeptidase activity
protein binding
enzyme binding
protein domain specific binding
cysteine-type endopeptidase activity involved in apoptotic process