s25740

• Gene Symbol: LAT
• Gene Name: linker for activation of T-cells
• Gene Aliases: LAT1, pp36
• Chromosome Location: Chr.16: 28984826 - 28990783 on Build GRCh38
• UniGene ID: Hs.632179
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: LAT
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001014987.1	NP_001014987.1	2, 3	481
	NM_001014988.1	NP_001014988.1	2, 3	481
	NM_001014989.1	NP_001014989.2	3, 4	273
	NM_014387.3	NP_055202.1	2, 3	481
GenBank mRNA	AF036905.1	-	2, 3	186
	AF036906.1	-	2, 3	207
	AJ223280.1	-	2, 3	451
	AK307342.1	-	2, 3	498
	BC011563.1	-	3, 4	273	4644259
	BI769296.1	-	2, 3	482
	BI911769.1	-	2, 3	448
	FN432831.1	-	2, 3	129
	FN432832.1	-	2, 3	129
	FN432833.1	-	2, 3	129
	FN432834.1	-	2, 3	129

More Information

Gene Ontology Categories:

Process(es)

MAPK cascade
adaptive immune response
lymphocyte homeostasis
inflammatory response
immune response
integrin-mediated signaling pathway
Ras protein signal transduction
positive regulation of signal transduction
gene expression
calcium-mediated signaling
platelet activation
intracellular signal transduction
Fc-epsilon receptor signaling pathway
T cell activation
mast cell degranulation
positive regulation of GTPase activity
positive regulation of protein kinase activity
T cell receptor signaling pathway
regulation of T cell activation

Function(s)

SH3/SH2 adaptor activity
Ras guanyl-nucleotide exchange factor activity
protein binding
protein kinase binding