s26193 Validated

• Gene Symbol: RABGEF1
• Gene Name: RAB guanine nucleotide exchange factor 1
• Gene Aliases: RABEX5, RAP1, rabex-5
• Chromosome Location: Chr.7: 66682091 - 66811464 on Build GRCh38
• UniGene ID: Hs.530053
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: RABGEF1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001287060.1	NP_001273989.1	7	1489
	NM_001287061.1	NP_001273990.1	6	829
	NM_001287062.1	NP_001273991.1	7	965
	NM_014504.2	NP_055319.1	6	770
GenBank mRNA	AJ250042.1	-	6	693
	AK001702.1	-	3	274
	AK056864.1	-	7	1416
	AK223329.1	-	6	693
	AK290678.1	-	7	888
	AK303006.1	-	6	826
	BC015330.1	-	6	716	4420279
	BT007107.1	-	5	616
	DQ230533.1	-	5	616
	DQ230534.1	-	6	736
	DQ230535.1	-	3	364

More Information

Matching Taqman Gene Expression Assay:

Hs00205696_m1

Panther Classification:

Molecular Function -

guanyl-nucleotide exchange factor

Gene Ontology Categories:

Process(es)

negative regulation of protein phosphorylation
negative regulation of leukocyte migration
protein targeting to membrane
endocytosis
protein ubiquitination
negative regulation of mast cell degranulation
positive regulation of GTPase activity
negative regulation of Ras protein signal transduction
negative regulation of receptor-mediated endocytosis
negative regulation of inflammatory response
regulation of Fc receptor mediated stimulatory signaling pathway
negative regulation of interleukin-6 secretion
negative regulation of Kit signaling pathway

Function(s)

DNA binding
protein binding
zinc ion binding
Rab guanyl-nucleotide exchange factor activity
Rab GTPase binding
ubiquitin protein ligase activity