s2765

• Gene Symbol: CDC42
• Gene Name: cell division cycle 42
• Gene Aliases: CDC42Hs, G25K, TKS
• Chromosome Location: Chr.1: 22052627 - 22092943 on Build GRCh38
• UniGene ID: Hs.467637
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: CDC42
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001039802.1	NP_001034891.1	3	333
	NM_001791.3	NP_001782.1	2	207
	NM_044472.2	NP_426359.1	2	207
GenBank mRNA	AF498962.1	-	1	41
	AF498963.1	-	1	41
	AK297465.1	-	1	114
	AK303994.1	-	2	123
	AK311375.1	-	2	125
	AK316449.1	-	2	124
	AL121734.1	-	2	145
	AL121735.1	-	2	145
	AL121736.1	-	3	202
	AL121737.1	-	2	276
	BC002711.2	-	2	145	3626647
	BC003682.1	-	1	94	3457085
	BC018266.1	-	3	292	3449526
	BP871988.1	-	2	207
	M35543.1	-	1	44
	M57298.1	-	2	110

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_171994, XM_008764286, XM_008764287, FQ231846, FQ232179, and others.
This siRNA also targets the following transcripts in Mouse: NM_001243769, NM_009861, AK151726, AK153564, AK167609, and others.

Panther Classification:

Molecular Function -

small GTPase

Gene Ontology Categories:

Process(es)

sprouting angiogenesis
cardiac conduction system development
keratinocyte development
Golgi organization
regulation of mitotic nuclear division
nuclear migration
establishment or maintenance of cell polarity
small GTPase mediated signal transduction
blood coagulation
positive regulation of gene expression
negative regulation of gene expression
protein ubiquitination
substantia nigra development
actin cytoskeleton organization
macrophage differentiation
positive regulation of cell growth
hair follicle morphogenesis
positive regulation of pseudopodium assembly
T cell costimulation
negative regulation of protein complex assembly
keratinization
regulation of protein stability
positive regulation of cytokinesis
positive regulation of peptidyl-serine phosphorylation
adherens junction organization
cellular protein localization
establishment or maintenance of apical/basal cell polarity
multicellular organism growth
dendritic cell migration
Fc-gamma receptor signaling pathway involved in phagocytosis
negative regulation of epidermal growth factor receptor signaling pathway
regulation of protein catabolic process
regulation of protein heterodimerization activity
positive regulation of neuron apoptotic process
positive regulation of phosphatidylinositol 3-kinase activity
positive regulation of DNA replication
regulation of protein kinase activity
positive regulation of JNK cascade
filopodium assembly
vascular endothelial growth factor receptor signaling pathway
ephrin receptor signaling pathway
neuron fate determination
actin filament bundle assembly
regulation of small GTPase mediated signal transduction
positive regulation of muscle cell differentiation
regulation of filopodium assembly
establishment of Golgi localization
positive regulation of synapse structural plasticity
regulation of attachment of spindle microtubules to kinetochore
heart contraction
canonical Wnt signaling pathway
Wnt signaling pathway, planar cell polarity pathway
positive regulation of epithelial cell proliferation involved in lung morphogenesis
submandibular salivary gland formation
epithelial-mesenchymal cell signaling
hair follicle placode formation
positive regulation of hair follicle cell proliferation
organelle transport along microtubule
actin filament branching
epithelial cell-cell adhesion
positive regulation of intracellular protein transport
positive regulation of substrate adhesion-dependent cell spreading

Function(s)

GTPase activity
protein binding
GTP binding
protein kinase binding
GTP-dependent protein binding
mitogen-activated protein kinase kinase kinase binding
thioesterase binding
apolipoprotein A-I receptor binding
identical protein binding
Rho GDP-dissociation inhibitor binding
ubiquitin protein ligase activity