s29229 Validated

Gene Symbol:

EGLN1 SCAND2P

Gene Name:

egl-9 family hypoxia inducible factor 1

SCAN domain containing 2 pseudogene

Gene Aliases:

C1orf12, ECYT3, HALAH, HIF-PH2, HIFPH2, HPH-2, HPH2, PHD2, SM20, ZMYND6

SCAND2

Chromosome Location:

Chr.1: 231363751 - 231425044 on Build GRCh38

Chromosome Location:

Chr.15: 84631460 - 84642463 on Build GRCh38

UniGene ID:

Hs.444450

Hs.658114

Species:

Human

Species Specific ID (Flybase ID):

-

-

siRNA Details

Gene Symbol: EGLN1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_022051.2	NP_071334.1	4	4316
	XM_005273167.4	XP_005273224.1	3	1465
GenBank mRNA	AF229245.1	-	4	4316
	AF277174.1	-	4	274
	AJ310543.1	-	4	1256
	AL833885.1	-	4	684
	BC005369.1	-	4	348
	DQ975380.1	-	4	405

Gene Symbol: SCAND2P
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
GenBank mRNA	AF229246.1	-	2	1561
	AL109690.1	-	1	301

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_053207, BC006903, AJ310546, AF453878.

Matching Taqman Gene Expression Assay:

Hs00254392_m1

Panther Classification:

Molecular Function -

C2H2 zinc finger transcription factor

Gene Ontology Categories:

Process(es)

response to hypoxia
peptidyl-proline hydroxylation to 4-hydroxy-L-proline
negative regulation of cAMP catabolic process
oxygen homeostasis
negative regulation of sequence-specific DNA binding transcription factor activity
regulation of angiogenesis
negative regulation of cyclic-nucleotide phosphodiesterase activity
cardiac muscle tissue morphogenesis
oxidation-reduction process
heart trabecula formation
ventricular septum morphogenesis
labyrinthine layer development
regulation of transcription from RNA polymerase II promoter in response to hypoxia
response to nitric oxide

Function(s)

iron ion binding
protein binding
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
enzyme binding
L-ascorbic acid binding
peptidyl-proline dioxygenase activity
peptidyl-proline 4-dioxygenase activity