s29922

• Gene Symbol: PINX1
• Gene Name: PIN2/TERF1 interacting, telomerase inhibitor 1
• Gene Aliases: LPTL, LPTS
• Chromosome Location: Chr.8: 10764961 - 10839899 on Build GRCh38
• UniGene ID: Hs.490991
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: PINX1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001284356.1	NP_001271285.1	5	474
	NM_017884.5	NP_060354.4	5	474
GenBank mRNA	AF205718.1	-	5	463
	AF418553.1	-	5	463
	AJ344104.1	-	5	463
	AK313715.1	-	5	412
	AY238941.1	-	5	356
	AY523566.1	-	5	356
	BC015479.1	-	5	420	3914396
	BC093762.1	-	5	364	7939607
	CB125276.1	-	5	474

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001083337, XM_006252181, BC158553, FQ232228, EF446165.
This siRNA also targets the following transcripts in Mouse: NM_028228, AK012057, AJ344106, AK075840, BC115636, and others.

Panther Classification:

Molecular Function -

HMG box transcription factor, RNA metabolism protein, nucleic acid metabolism protein

Gene Ontology Categories:

Process(es)

telomere maintenance via telomerase
mitotic metaphase plate congression
negative regulation of cell proliferation
negative regulation of protein ubiquitination
regulation of protein stability
negative regulation of telomere maintenance via telomerase
regulation of telomerase activity
negative regulation of telomerase activity
protein localization to chromosome, telomeric region
protein localization to nucleolus
negative regulation of telomere maintenance via telomere lengthening
positive regulation of telomeric DNA binding
positive regulation of protein localization to nucleolus

Function(s)

protein binding
telomerase inhibitor activity
telomerase RNA binding