s3385

• Gene Symbol: MAP3K8
• Gene Name: mitogen-activated protein kinase kinase kinase 8
• Gene Aliases: AURA2, COT, EST, ESTF, MEKK8, TPL2, Tpl-2, c-COT
• Chromosome Location: Chr.10: 30434021 - 30461833 on Build GRCh38
• UniGene ID: Hs.432453
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: MAP3K8
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001244134.1	NP_001231063.1	7	1640
	NM_001320961.1	NP_001307890.1	7	1396
	NM_005204.3	NP_005195.2	8	1871
	XM_017015707.1	XP_016871196.1	7	2088
	XM_017015708.1	XP_016871197.1	8	1601
	XM_017015709.1	XP_016871198.1	7	4381
	XM_017015710.1	XP_016871199.1	7	1491
	XM_017015711.1	XP_016871200.1	7	5450
	XM_017015712.1	XP_016871201.1	8	4963
	XM_017015713.1	XP_016871202.1	8	5207
	XM_017015714.1	XP_016871203.1	7	5002
GenBank mRNA	AK290320.1	-	7	1536
	AK313295.1	-	7	1537
	BC104833.1	-	7	1497	8143836
	BC113566.1	-	7	1497	8322618
	CR542284.1	-	6	1259
	D14497.1	-	8	1625
	Z14138.1	-	6	1419

More Information

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

activation of MAPKK activity
protein phosphorylation
apoptotic process
cell cycle
T cell costimulation
stress-activated MAPK cascade

Function(s)

magnesium ion binding
protein serine/threonine kinase activity
receptor signaling protein serine/threonine kinase activity
MAP kinase kinase kinase activity
protein binding
ATP binding