s339 Validated

• Gene Symbol: UBB
• Gene Name: ubiquitin B
• Gene Aliases: HEL-S-50
• Chromosome Location: Chr.17: 16380793 - 16382745 on Build GRCh38
• UniGene ID: Hs.356190
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: UBB
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001281716.1	NP_001268645.1	2	1027
	NM_001281717.1	NP_001268646.1	2	998
	NM_001281718.1	NP_001268647.1	2	958
	NM_001281719.1	NP_001268648.1	2	956
	NM_001281720.1	NP_001268649.1	2	802
	NM_018955.3	NP_061828.1	2	1171
GenBank mRNA	AK129498.1	-	2	873
	AK300882.1	-	3	649
	BC000379.2	-	2	915	2820408
	BC009301.2	-	2	861	4126622
	BC015127.1	-	2	877	3929901
	BC026301.1	-	2	873	4280629
	BC031027.1	-	2	875	4715377
	BC038999.1	-	2	884	4943285
	BC046123.2	-	2	863	3879581
	GQ472200.1	-	2	915

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_138895, XM_003750018, D16554, BC070919, BC078726, and others.

Matching Taqman Gene Expression Assay:

Hs00430290_m1

Gene Ontology Categories:

Process(es)

G2/M transition of mitotic cell cycle
negative regulation of transcription from RNA polymerase II promoter
MAPK cascade
activation of MAPK activity
protein polyubiquitination
nucleotide-excision repair, DNA damage recognition
nucleotide-excision repair, DNA duplex unwinding
stimulatory C-type lectin receptor signaling pathway
MyD88-dependent toll-like receptor signaling pathway
MyD88-independent toll-like receptor signaling pathway
glycogen biosynthetic process
transcription-coupled nucleotide-excision repair
nucleotide-excision repair, preincision complex assembly
nucleotide-excision repair, DNA incision, 5'-to lesion
nucleotide-excision repair, DNA gap filling
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
transforming growth factor beta receptor signaling pathway
Notch signaling pathway
I-kappaB kinase/NF-kappaB signaling
JNK cascade
fibroblast growth factor receptor signaling pathway
regulation of tumor necrosis factor-mediated signaling pathway
regulation of necrotic cell death
Wnt signaling pathway
endosomal transport
macroautophagy
viral life cycle
virion assembly
translesion synthesis
negative regulation of transforming growth factor beta receptor signaling pathway
anaphase-promoting complex-dependent catabolic process
positive regulation of protein ubiquitination
regulation of type I interferon production
negative regulation of type I interferon production
tumor necrosis factor-mediated signaling pathway
nucleotide-excision repair, DNA incision
ion transmembrane transport
TRIF-dependent toll-like receptor signaling pathway
interstrand cross-link repair
NIK/NF-kappaB signaling
Fc-epsilon receptor signaling pathway
ERBB2 signaling pathway
negative regulation of epidermal growth factor receptor signaling pathway
error-prone translesion synthesis
DNA damage response, detection of DNA damage
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
positive regulation of apoptotic process
negative regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
proteasome-mediated ubiquitin-dependent protein catabolic process
regulation of mRNA stability
cellular protein metabolic process
innate immune response
positive regulation of epidermal growth factor receptor signaling pathway
positive regulation of transcription from RNA polymerase II promoter
mitochondrion transport along microtubule
neuron projection morphogenesis
T cell receptor signaling pathway
positive regulation of NF-kappaB transcription factor activity
stress-activated MAPK cascade
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
regulation of mitochondrial membrane potential
Wnt signaling pathway, planar cell polarity pathway
regulation of proteasomal protein catabolic process
regulation of transcription from RNA polymerase II promoter in response to hypoxia
nucleotide-binding oligomerization domain containing signaling pathway
global genome nucleotide-excision repair
error-free translesion synthesis
intracellular transport of virus
negative regulation of canonical Wnt signaling pathway
positive regulation of canonical Wnt signaling pathway
regulation of neuron death
regulation of signal transduction by p53 class mediator
positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator
positive regulation of protein monoubiquitination

Function(s)

protein binding