s3493

• Gene Symbol: ATF2
• Gene Name: activating transcription factor 2
• Gene Aliases: CRE-BP1, CREB-2, CREB2, HB16, TREB7
• Chromosome Location: Chr.2: 175072250 - 175168206 on Build GRCh38
• UniGene ID: Hs.592510
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: ATF2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001256090.1	NP_001243019.1	9	923
	NM_001256091.1	NP_001243020.1	8	848
	NM_001256092.1	NP_001243021.1	7	791
	NM_001256093.1	NP_001243022.1	7	791
	NM_001256094.1	NP_001243023.1	8	888
	NM_001880.3	NP_001871.2	8	888
	NR_045768.1		9	923
	NR_045769.1		9	923
	NR_045770.1		9	923
	NR_045771.1		8	888
	NR_045772.1		8	826
	NR_045773.1		7	791
	NR_045774.1		8	888
GenBank mRNA	AK128731.1	-	8	788
	BC026175.1	-	8	855
	BC107698.1	-	7	758	6456836
	BC130335.1	-	7	654	40146366
	BC130337.1	-	7	654	40146368
	BX648469.1	-	7	678
	DQ003036.1	-	9	886
	DQ003037.1	-	8	851
	DQ003039.1	-	8	851
	DQ003040.1	-	8	789
	DQ003041.1	-	9	886
	DQ003042.1	-	8	789
	DQ003043.1	-	9	886
	DQ003044.1	-	9	886
	DQ003045.1	-	7	754
	DQ003046.1	-	7	754
	DQ003047.1	-	8	851
	DQ003048.1	-	7	754
	DQ003049.1	-	8	811
	X15875.1	-	6	615

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_031018, U38938.
This siRNA also targets the following transcripts in Mouse: NM_001025093, NM_001284371, NM_001284374, NM_001284370, NM_001284369, and others.

Panther Classification:

Molecular Function -

basic leucine zipper transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
outflow tract morphogenesis
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
response to osmotic stress
cellular response to DNA damage stimulus
response to water deprivation
histone acetylation
intra-S DNA damage checkpoint
positive regulation of transforming growth factor beta2 production
positive regulation of neuron apoptotic process
fat cell differentiation
positive regulation of transcription from RNA polymerase II promoter
negative regulation of epithelial cell proliferation
regulation of sequence-specific DNA binding transcription factor activity
positive regulation of sequence-specific DNA binding transcription factor activity
adipose tissue development
amelogenesis
positive regulation of mitochondrial membrane permeability involved in apoptotic process

Function(s)

RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
transcription factor activity, RNA polymerase II transcription factor binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II activating transcription factor binding
enhancer sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
transcription coactivator activity
histone acetyltransferase activity
protein binding
cAMP response element binding protein binding
protein kinase binding
cAMP response element binding
metal ion binding
protein heterodimerization activity