s3898 Validated

• Gene Symbol: DAB2
• Gene Name: DAB2, clathrin adaptor protein
• Gene Aliases: DOC-2, DOC2
• Chromosome Location: Chr.5: 39371674 - 39425233 on Build GRCh38
• UniGene ID: Hs.696631
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: DAB2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001244871.1	NP_001231800.1	9	1205
	NM_001343.3	NP_001334.2	10	1268
GenBank mRNA	AF188298.1	-	8	762
	AK297984.1	-	5	319
	AK314381.1	-	10	1016
	BC003064.2	-	10	864	3504380
	L16886.1	-	8	608
	U39050.1	-	9	836
	U53446.1	-	10	881

More Information

Matching Taqman Gene Expression Assay:

Hs00184598_m1

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

positive regulation of protein phosphorylation
receptor-mediated endocytosis
apoptotic process
integrin-mediated signaling pathway
multicellular organism development
cell proliferation
positive regulation of epithelial to mesenchymal transition
positive regulation of pathway-restricted SMAD protein phosphorylation
protein transport
Wnt signaling pathway
positive regulation of cell migration
positive regulation of transforming growth factor beta receptor signaling pathway
negative regulation of protein binding
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
leading edge cell differentiation
negative regulation of apoptotic process
positive regulation of endocytosis
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of SMAD protein import into nucleus
negative regulation of androgen receptor signaling pathway
negative regulation of canonical Wnt signaling pathway
negative regulation of protein localization to plasma membrane
positive regulation of Wnt signaling pathway, planar cell polarity pathway
positive regulation of clathrin-mediated endocytosis
positive regulation of early endosome to late endosome transport

Function(s)

protein binding
protein C-terminus binding
clathrin adaptor activity
cargo receptor activity
SMAD binding