s397 Validated

• Gene Symbol: CASP3
• Gene Name: caspase 3
• Gene Aliases: CPP32, CPP32B, SCA-1
• Chromosome Location: Chr.4: 184627696 - 184649475 on Build GRCh38
• UniGene ID: Hs.141125
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: CASP3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_004346.3	NP_004337.2	4	359
	NM_032991.2	NP_116786.1	3	192
	XM_011532301.1	XP_011530603.1	4	293
GenBank mRNA	AK291337.1	-	4	330
	AU127028.1	-	3	192
	AU133051.1	-	4	331
	BC016926.2	-	4	311	4419175
	BX647609.1	-	4	431
	U13737.1	-	4	320
	U13738.1	-	3	159
	U26943.1	-	2	96

More Information

Matching Taqman Gene Expression Assay:

Hs00234387_m1

Panther Classification:

Molecular Function -

protease

Gene Ontology Categories:

Process(es)

response to hypoxia
B cell homeostasis
apoptotic DNA fragmentation
proteolysis
apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
cellular component disassembly involved in execution phase of apoptosis
cellular response to DNA damage stimulus
heart development
sensory perception of sound
learning or memory
activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c
response to UV
response to glucose
response to X-ray
regulation of macroautophagy
protein processing
hippocampus development
neuron differentiation
keratinocyte differentiation
erythrocyte differentiation
platelet formation
negative regulation of B cell proliferation
response to cobalt ion
response to estradiol
response to lipopolysaccharide
glial cell apoptotic process
response to tumor necrosis factor
response to nicotine
hippo signaling
wound healing
response to drug
response to hydrogen peroxide
T cell homeostasis
negative regulation of apoptotic process
response to amino acid
positive regulation of neuron apoptotic process
cell fate commitment
negative regulation of cyclin-dependent protein serine/threonine kinase activity
negative regulation of activated T cell proliferation
response to antibiotic
neurotrophin TRK receptor signaling pathway
response to glucocorticoid
neuron apoptotic process
cellular response to organic cyclic compound
apoptotic signaling pathway
extrinsic apoptotic signaling pathway in absence of ligand
execution phase of apoptosis

Function(s)

protease binding
aspartic-type endopeptidase activity
cysteine-type endopeptidase activity
cyclin-dependent protein serine/threonine kinase inhibitor activity
death receptor binding
protein binding
peptidase activity
cysteine-type endopeptidase activator activity involved in apoptotic process
phospholipase A2 activator activity
protein complex binding
cysteine-type endopeptidase activity involved in apoptotic process
cysteine-type endopeptidase activity involved in execution phase of apoptosis