s4155

• Gene Symbol: DMD
• Gene Name: dystrophin
• Gene Aliases: BMD, CMD3B, DXS142, DXS164, DXS206, DXS230, DXS239, DXS268, DXS269, DXS270, DXS272, MRX85
• Chromosome Location: Chr.X: 31119219 - 33339609 on Build GRCh38
• UniGene ID: Hs.495912
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: DMD
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000109.3	NP_000100.2	63, 64	9607
	NM_004006.2	NP_003997.1	63, 64	9531
	NM_004009.3	NP_004000.1	63, 64	9538
	NM_004010.3	NP_004001.1	63, 64	9621
	NM_004011.3	NP_004002.2	35, 36	5309
	NM_004012.3	NP_004003.1	35, 36	5452
	NM_004013.2	NP_004004.1	20, 21	2948
	NM_004014.2	NP_004005.1	9, 10	1161
	NM_004015.2	NP_004006.1	2, 3	161
	NM_004016.2	NP_004007.1	2, 3	161
	NM_004017.2	NP_004008.1	2, 3	161
	NM_004018.2	NP_004009.1	2, 3	161
	NM_004019.2	NP_004010.1	2, 3	161
	NM_004020.3	NP_004011.2	20, 21	2948
	NM_004021.2	NP_004012.1	20, 21	2948
	NM_004022.2	NP_004013.1	20, 21	2948
	NM_004023.2	NP_004014.1	20, 21	2948
	XM_006724468.2	XP_006724531.1	63, 64	9484
	XM_006724469.3	XP_006724532.1	63, 64	9458
	XM_006724470.3	XP_006724533.1	63, 64	9484
	XM_006724473.2	XP_006724536.1	62, 63	9346
	XM_006724474.3	XP_006724537.1	63, 64	9484
	XM_006724475.2	XP_006724538.1	63, 64	9484
	XM_011545467.1	XP_011543769.1	62, 63	9361
	XM_011545468.2	XP_011543770.1	63, 64	9484
	XM_017029328.1	XP_016884817.1	63, 64	9484
	XM_017029331.1	XP_016884820.1	23, 24	4060
GenBank mRNA	AB208836.1	-	17, 18	2395
	AK299936.1	-	2, 3	203
	BC028720.1	-	2, 3	212
	BC070078.1	-	2, 3	162
	BC094758.1	-	2, 3	175
	BC127103.1	-	17, 18	2472
	BC150141.1	-	17, 18	2472
	DB233002.1	-	2, 3	161
	KU178030.1	-	2, 3	83
	KU178031.1	-	2, 3	83
	KU178032.1	-	2, 3	83
	KU178033.1	-	2, 3	83
	KU178034.1	-	2, 3	83
	M18533.1	-	63, 64	9495
	M92650.1	-	2, 3	135
	S38776.1	-	2, 3	206
	X14298.1	-	63, 64	9385

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001005246, XM_008773253, XM_008773252, X65468, X69767, and others.
This siRNA also targets the following transcripts in Mouse: NM_007868, KJ480729, S62620, KJ480728, M68859, and others.

Panther Classification:

Molecular Function -

ubiquitin-protein ligase

Gene Ontology Categories:

Process(es)

regulation of heart rate
cytoskeleton organization
muscle organ development
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion
regulation of skeletal muscle contraction
muscle attachment
muscle filament sliding
negative regulation of peptidyl-serine phosphorylation
cellular protein localization
response to muscle stretch
peptide biosynthetic process
cellular protein complex assembly
muscle cell cellular homeostasis
muscle fiber development
cardiac muscle contraction
regulation of ryanodine-sensitive calcium-release channel activity
cardiac muscle cell action potential
regulation of voltage-gated calcium channel activity
negative regulation of peptidyl-cysteine S-nitrosylation
positive regulation of sodium ion transmembrane transporter activity

Function(s)

dystroglycan binding
actin binding
structural constituent of cytoskeleton
protein binding
zinc ion binding
structural constituent of muscle
myosin binding
vinculin binding
nitric-oxide synthase binding