s4286

• Gene Symbol: DRD2
• Gene Name: dopamine receptor D2
• Gene Aliases: D2DR, D2R
• Chromosome Location: Chr.11: 113409595 - 113475279 on Build GRCh38
• UniGene ID: Hs.73893
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: DRD2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000795.3	NP_000786.1	3	532
	NM_016574.3	NP_057658.2	3	532
	XM_017017296.1	XP_016872785.1	3	514
GenBank mRNA	AB451480.1	-	2	297
	AF176812.1	-	2	306
	AK308777.1	-	3	362
	BC021195.2	-	3	392	3939741
	BF437994.1	-	3	364
	M29066.1	-	2	330
	M30625.1	-	3	633
	S62137.1	-	2	614
	S69899.1	-	3	396
	X51362.1	-	3	462
	X51645.1	-	2	325

More Information

• Set Membership: G-protein coupled receptor

Panther Classification:

Molecular Function -

G-protein coupled receptor

Gene Ontology Categories:

Process(es)

temperature homeostasis
response to hypoxia
synaptic transmission, dopaminergic
response to amphetamine
neurological system process involved in regulation of systemic arterial blood pressure
regulation of heart rate
regulation of sodium ion transport
G-protein coupled receptor internalization
positive regulation of neuroblast proliferation
positive regulation of receptor internalization
negative regulation of adenylate cyclase activity
adenylate cyclase-inhibiting dopamine receptor signaling pathway
neuron-neuron synaptic transmission
axonogenesis
synapse assembly
sensory perception of smell
long-term memory
grooming behavior
locomotory behavior
adult walking behavior
feeding behavior
protein localization
negative regulation of cell proliferation
associative learning
visual learning
response to light stimulus
response to toxic substance
response to iron ion
regulation of dopamine secretion
response to inactivity
Wnt signaling pathway
striatum development
orbitofrontal cortex development
cerebral cortex GABAergic interneuron migration
adenohypophysis development
negative regulation of cell migration
peristalsis
regulation of cAMP metabolic process
auditory behavior
activation of protein kinase activity
regulation of synaptic transmission, GABAergic
positive regulation of cytokinesis
circadian regulation of gene expression
negative regulation of dopamine secretion
response to histamine
response to nicotine
positive regulation of urine volume
positive regulation of renal sodium excretion
positive regulation of multicellular organism growth
response to cocaine
negative regulation of circadian sleep/wake cycle, sleep
dopamine metabolic process
response to drug
regulation of potassium ion transport
response to morphine
pigmentation
regulation of phosphoprotein phosphatase activity
positive regulation of G-protein coupled receptor protein signaling pathway
negative regulation of blood pressure
negative regulation of innate immune response
positive regulation of transcription from RNA polymerase II promoter
phosphatidylinositol metabolic process
negative regulation of insulin secretion
acid secretion
behavioral response to cocaine
behavioral response to ethanol
regulation of long-term neuronal synaptic plasticity
response to axon injury
branching morphogenesis of a nerve
arachidonic acid secretion
negative regulation of protein secretion
release of sequestered calcium ion into cytosol
negative regulation of cytosolic calcium ion concentration
regulation of dopamine uptake involved in synaptic transmission
positive regulation of dopamine uptake involved in synaptic transmission
regulation of synapse structural plasticity
negative regulation of protein kinase B signaling
negative regulation of synaptic transmission, glutamatergic
positive regulation of growth hormone secretion
prepulse inhibition
phospholipase C-activating dopamine receptor signaling pathway
negative regulation of dopamine receptor signaling pathway
positive regulation of ERK1 and ERK2 cascade
adenylate cyclase-activating adrenergic receptor signaling pathway
regulation of locomotion involved in locomotory behavior
chemical synaptic transmission, postsynaptic
positive regulation of glial cell-derived neurotrophic factor secretion
positive regulation of long-term synaptic potentiation
negative regulation of voltage-gated calcium channel activity

Function(s)

dopamine neurotransmitter receptor activity, coupled via Gi/Go
adrenergic receptor activity
protein binding
drug binding
dopamine binding
ionotropic glutamate receptor binding
identical protein binding
protein homodimerization activity
protein heterodimerization activity