s4447 Validated

• Gene Symbol: S1PR1
• Gene Name: sphingosine-1-phosphate receptor 1
• Gene Aliases: CD363, CHEDG1, D1S3362, ECGF1, EDG-1, EDG1, S1P1
• Chromosome Location: Chr.1: 101236749 - 101241520 on Build GRCh38
• UniGene ID: Hs.154210
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: S1PR1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001320730.1	NP_001307659.1	2	1031
	NM_001400.4	NP_001391.2	2	1139
GenBank mRNA	AF022137.1	-	1	625
	AF233365.1	-	1	625
	AK297005.1	-	2	877
	AK312493.1	-	2	869
	BC018650.1	-	2	873	4071217
	CR541786.1	-	1	625
	CR542269.1	-	1	625
	M31210.1	-	2	875

More Information

• Set Membership: G-protein coupled receptor

Matching Taqman Gene Expression Assay:

Hs00173499_m1

Panther Classification:

Molecular Function -

G-protein coupled receptor

Gene Ontology Categories:

Process(es)

angiogenesis
blood vessel maturation
cardiac muscle tissue growth involved in heart morphogenesis
sphingosine-1-phosphate signaling pathway
chemotaxis
cell adhesion
G-protein coupled receptor signaling pathway
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
brain development
cell migration
transmission of nerve impulse
lamellipodium assembly
regulation of cell adhesion
neuron differentiation
positive regulation of cell migration
regulation of bone mineralization
actin cytoskeleton reorganization
positive regulation of GTPase activity
regulation of bone resorption
endothelial cell differentiation
positive regulation of transcription from RNA polymerase II promoter
positive regulation of smooth muscle cell proliferation
positive regulation of positive chemotaxis
positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
negative regulation of stress fiber assembly
heart trabecula morphogenesis
T cell migration

Function(s)

G-protein coupled receptor binding
G-protein coupled receptor activity
sphingosine-1-phosphate receptor activity
sphingolipid binding