s4457

• Gene Symbol: EDN1
• Gene Name: endothelin 1
• Gene Aliases: ARCND3, ET1, HDLCQ7, PPET1, QME
• Chromosome Location: Chr.6: 12256464 - 12297194 on Build GRCh38
• UniGene ID: Hs.511899
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: EDN1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001168319.1	NP_001161791.1	4	844
	NM_001955.4	NP_001946.3	4	847
	XM_011514330.2	XP_011512632.1	5	603
	XM_011514331.2	XP_011512633.1	6	764
	XM_011514332.2	XP_011512634.1	5	601
	XM_017010331.1	XP_016865820.1	5	787
GenBank mRNA	AK226096.1	-	4	762
	AK291838.1	-	4	784
	AK313914.1	-	4	779
	BC009720.1	-	4	716	3900704
	BX439515.2	-	4	807
	CR541903.1	-	4	513
	S56805.1	-	4	849
	Y00749.1	-	4	765

More Information

Panther Classification:

Molecular Function -

peptide hormone

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
prostaglandin biosynthetic process
patterning of blood vessels
in utero embryonic development
histamine secretion
regulation of systemic arterial blood pressure by endothelin
regulation of pH
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
protein kinase C-activating G-protein coupled receptor signaling pathway
cell-cell signaling
heart development
respiratory gaseous exchange
body fluid secretion
positive regulation of cell proliferation
dorsal/ventral pattern formation
response to ozone
multicellular organism aging
positive regulation of heart rate
positive regulation of endothelial cell migration
positive regulation of cardiac muscle hypertrophy
positive regulation of receptor biosynthetic process
neural crest cell development
phosphatidylinositol 3-kinase signaling
response to activity
artery smooth muscle contraction
vein smooth muscle contraction
glucose transport
cell growth
regulation of vasoconstriction
sensory perception of pain
calcium-mediated signaling
peptide hormone secretion
nitric oxide transport
negative regulation of blood coagulation
positive regulation of cell migration
neutrophil chemotaxis
negative regulation of cAMP biosynthetic process
phospholipase D-activating G-protein coupled receptor signaling pathway
negative regulation of cellular protein metabolic process
positive regulation of prostaglandin secretion
response to lipopolysaccharide
response to testosterone
negative regulation of smooth muscle cell apoptotic process
response to prostaglandin F
response to nicotine
cellular response to drug
positive regulation of urine volume
positive regulation of renal sodium excretion
response to muscle stretch
epithelial fluid transport
vasoconstriction
protein kinase C deactivation
middle ear morphogenesis
positive regulation of odontogenesis
superoxide anion generation
rhythmic excitation
response to amino acid
positive regulation of MAP kinase activity
positive regulation of JUN kinase activity
response to leptin
leukocyte activation
positive regulation of nitric oxide biosynthetic process
positive regulation of cell size
positive regulation of mitotic nuclear division
positive regulation of transcription from RNA polymerase II promoter
positive regulation of smooth muscle contraction
positive regulation of hormone secretion
negative regulation of hormone secretion
inositol phosphate-mediated signaling
positive regulation of smooth muscle cell proliferation
positive regulation of sequence-specific DNA binding transcription factor activity
cartilage development
positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
negative regulation of nitric-oxide synthase biosynthetic process
membrane depolarization
regulation of sensory perception of pain
maternal process involved in parturition
positive regulation of sarcomere organization
positive regulation of prostaglandin-endoperoxide synthase activity
positive regulation of cell growth involved in cardiac muscle cell development
positive regulation of chemokine-mediated signaling pathway
cellular response to calcium ion
cellular response to interferon-gamma
cellular response to interleukin-1
cellular response to tumor necrosis factor
cellular response to peptide hormone stimulus
cellular response to glucocorticoid stimulus
cellular response to mineralocorticoid stimulus
cellular response to fatty acid
cellular response to hypoxia
response to dexamethasone
cellular response to transforming growth factor beta stimulus
response to salt

Function(s)

cytokine activity
hormone activity
protein binding
endothelin A receptor binding
endothelin B receptor binding