s45115

• Gene Symbol: TICAM1
• Gene Name: toll like receptor adaptor molecule 1
• Gene Aliases: IIAE6, MyD88-3, PRVTIRB, TICAM-1, TRIF
• Chromosome Location: Chr.19: 4815924 - 4831742 on Build GRCh38
• UniGene ID: Hs.29344
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: TICAM1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_182919.3	NP_891549.1	2	1278
GenBank mRNA	AB086380.1	-	1	1072
	AB093555.1	-	1	1010
	AB097023.1	-	1	1010
	AB446484.1	-	1	1010
	AF070530.1	-	1	124
	AF492646.1	-	1	598
	BC136556.1	-	1	1064	9020546
	BC136557.1	-	1	1064	9020547

More Information

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

macrophage activation involved in immune response
MyD88-independent toll-like receptor signaling pathway
inflammatory response
I-kappaB kinase/NF-kappaB signaling
positive regulation of B cell proliferation
positive regulation of protein ubiquitination
lipopolysaccharide-mediated signaling pathway
positive regulation of protein binding
positive regulation of interleukin-6 production
positive regulation of tumor necrosis factor production
positive regulation of natural killer cell activation
negative regulation of MyD88-independent toll-like receptor signaling pathway
TRIF-dependent toll-like receptor signaling pathway
positive regulation of I-kappaB kinase/NF-kappaB signaling
response to exogenous dsRNA
regulation of protein homodimerization activity
positive regulation of chemokine biosynthetic process
innate immune response
positive regulation of interferon-beta biosynthetic process
positive regulation of nitric oxide biosynthetic process
positive regulation of NF-kappaB transcription factor activity
defense response to virus
necroptotic process
apoptotic signaling pathway

Function(s)

signal transducer activity
protein binding
protein kinase binding