s4538 Validated

• Gene Symbol: EGR1
• Gene Name: early growth response 1
• Gene Aliases: AT225, G0S30, KROX-24, NGFI-A, TIS8, ZIF-268, ZNF225
• Chromosome Location: Chr.5: 138465492 - 138469315 on Build GRCh38
• UniGene ID: Hs.326035
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: EGR1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001964.2	NP_001955.1	2	866
GenBank mRNA	AK301065.1	-	2	878
	BC073983.1	-	2	858	6188360
	KM114058.1	-	2	596
	M62829.1	-	2	850
	M80583.1	-	2	844
	X52541.1	-	2	866

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_012551, M18416, AY551092.

Matching Taqman Gene Expression Assay:

Hs00152928_m1

Panther Classification:

Molecular Function -

C2H2 zinc finger transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
response to glucose
T cell differentiation
BMP signaling pathway
response to insulin
regulation of protein sumoylation
skeletal muscle cell differentiation
regulation of apoptotic process
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
type I interferon signaling pathway
regulation of transcription from RNA polymerase II promoter in response to hypoxia
interleukin-1-mediated signaling pathway
cellular response to gamma radiation
cellular response to heparin
cellular response to mycophenolic acid
glomerular mesangial cell proliferation
positive regulation of glomerular metanephric mesangial cell proliferation
negative regulation of canonical Wnt signaling pathway

Function(s)

transcription regulatory region sequence-specific DNA binding
RNA polymerase II regulatory region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
histone acetyltransferase binding
sequence-specific DNA binding
metal ion binding