s501305

• Gene Symbol: ENG
• Gene Name: endoglin
• Gene Aliases: END, HHT1, ORW1
• Chromosome Location: Chr.9: 127815012 - 127854773 on Build GRCh38
• UniGene ID: Hs.76753
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: ENG
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000118.3	NP_000109.1	14	2248
	NM_001114753.2	NP_001108225.1	14	2248
	NM_001278138.1	NP_001265067.1	14	1988
GenBank mRNA	AK223044.1	-	7	811
	AK290389.1	-	14	2132
	AK300156.1	-	9	965
	AK301171.1	-	14	1988
	AK302455.1	-	11	1360
	BC014271.2	-	14	1982	3843174
	BT006872.1	-	14	1830
	J05481.1	-	14	1791
	X72012.1	-	14	2111

More Information

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

chronological cell aging
patterning of blood vessels
vasculogenesis
positive regulation of protein phosphorylation
heart looping
sprouting angiogenesis
endocardial cushion morphogenesis
cardiac ventricle morphogenesis
cardiac atrium morphogenesis
ventricular trabecula myocardium morphogenesis
cell migration involved in endocardial cushion formation
regulation of transcription, DNA-templated
cell adhesion
negative regulation of gene expression
positive regulation of pathway-restricted SMAD protein phosphorylation
regulation of transforming growth factor beta receptor signaling pathway
central nervous system vasculogenesis
negative regulation of cell migration
BMP signaling pathway
positive regulation of BMP signaling pathway
negative regulation of protein autophosphorylation
dorsal aorta morphogenesis
positive regulation of angiogenesis
positive regulation of transcription from RNA polymerase II promoter
smooth muscle tissue development
artery morphogenesis
venous blood vessel morphogenesis
endocardial cushion to mesenchymal transition
positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation

Function(s)

transmembrane signaling receptor activity
transforming growth factor beta receptor, cytoplasmic mediator activity
type II transforming growth factor beta receptor binding
protein binding
galactose binding
glycosaminoglycan binding
type I transforming growth factor beta receptor binding
BMP binding
protein homodimerization activity
activin binding
transforming growth factor beta binding