s501346

• Gene Symbol: MECP2
• Gene Name: methyl-CpG binding protein 2
• Gene Aliases: AUTSX3, MRX16, MRX79, MRXS13, MRXSL, PPMX, RS, RTS, RTT
• Chromosome Location: Chr.X: 154021800 - 154097731 on Build GRCh38
• UniGene ID: Hs.200716
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: MECP2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001110792.1	NP_001104262.1	3	569
	NM_001316337.1	NP_001303266.1	5	861
	NM_004992.3	NP_004983.1	4	693
	XM_005274682.4	XP_005274739.1	5	767
	XM_011531166.2	XP_011529468.1	3	580
	XM_017029533.1	XP_016885022.1	7	1193
GenBank mRNA	AF158180.1	-	4	634
	AJ132917.1	-	3	542
	AK289444.1	-	4	668
	AY541280.1	-	3	510
	BC011612.1	-	3	551	3956518
	BX538060.1	-	3	559
	GQ203293.1	-	4	693
	GQ203295.1	-	4	693
	GQ896382.1	-	4	693
	GU479943.1	-	4	693
	GU812285.1	-	3	467
	GU812286.1	-	3	467
	HM020402.1	-	4	693
	HM156732.1	-	4	693
	HM156733.1	-	4	693
	HQ127345.1	-	3	467
	HQ141377.1	-	3	467
	HQ141378.1	-	4	693
	HQ154629.1	-	4	693
	KU178174.1	-	3	467
	L37298.1	-	3	548
	X89430.1	-	2	438
	X99686.1	-	3	541
	Y12643.1	-	3	531

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: AF158181, AK158664, AJ132922, BC027153, AF072251, and others.

Panther Classification:

Molecular Function -

DNA metabolism protein

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
behavioral fear response
response to hypoxia
startle response
neurological system process involved in regulation of systemic arterial blood pressure
regulation of respiratory gaseous exchange by neurological system process
inositol metabolic process
mitochondrial electron transport, ubiquinol to cytochrome c
chromatin silencing
regulation of gene expression by genetic imprinting
transcription, DNA-templated
glutamine metabolic process
cellular biogenic amine metabolic process
synapse assembly
heart development
respiratory gaseous exchange
long-term memory
locomotory behavior
protein localization
glucocorticoid metabolic process
positive regulation of cell proliferation
adult locomotory behavior
visual learning
response to radiation
pathogenesis
post-embryonic development
response to ionizing radiation
response to lead ion
dendrite development
histone methylation
histone acetylation
proprioception
sensory perception of pain
cerebellum development
ventricular system development
negative regulation of histone methylation
cardiolipin metabolic process
response to estradiol
negative regulation of histone acetylation
social behavior
neuron maturation
negative regulation of neuron apoptotic process
regulation of DNA methylation
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
phosphatidylcholine metabolic process
negative regulation of astrocyte differentiation
catecholamine secretion
positive regulation of synapse assembly
excitatory postsynaptic potential
long-term synaptic potentiation

Function(s)

four-way junction DNA binding
DNA binding
transcription factor activity, sequence-specific DNA binding
transcription corepressor activity
mRNA binding
protein binding
transcription factor binding
methyl-CpG binding
double-stranded methylated DNA binding
protein domain specific binding
chromatin DNA binding
siRNA binding
histone deacetylase binding
poly(A) RNA binding
unmethylated CpG binding
protein N-terminus binding