s5103 Validated

• Gene Symbol: FEN1
• Gene Name: flap structure-specific endonuclease 1
• Gene Aliases: FEN-1, MF1, RAD2
• Chromosome Location: Chr.11: 61792637 - 61797244 on Build GRCh38
• UniGene ID: Hs.409065
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: FEN1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_004111.5	NP_004102.1	2	484
GenBank mRNA	AK312761.1	-	2	187
	BC000323.2	-	2	200	2821792
	BP244711.1	-	2	464
	BT019524.1	-	1	71
	CR536562.1	-	1	71
	L37374.1	-	1	71
	X76771.1	-	2	438

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_053430, XM_006231072, XM_008760246, XM_006231073, XM_006231074, and others.
This siRNA also targets the following transcripts in Mouse: NM_001271615, NM_001271614, NM_007999, L26320, AK187493, and others.

Matching Taqman Gene Expression Assay:

Hs00748727_s1

Panther Classification:

Molecular Function -

exodeoxyribonuclease

Gene Ontology Categories:

Process(es)

telomere maintenance via recombination
double-strand break repair via homologous recombination
DNA replication
DNA repair
base-excision repair
double-strand break repair
memory
UV protection
DNA replication, removal of RNA primer
RNA phosphodiester bond hydrolysis, endonucleolytic

Function(s)

magnesium ion binding
DNA binding
damaged DNA binding
double-stranded DNA binding
endonuclease activity
RNA-DNA hybrid ribonuclease activity
exonuclease activity
protein binding
double-stranded DNA exodeoxyribonuclease activity
5'-3' exonuclease activity
5'-flap endonuclease activity