s5176 Validated

• Gene Symbol: FGFR4
• Gene Name: fibroblast growth factor receptor 4
• Gene Aliases: CD334, JTK2, TKF
• Chromosome Location: Chr.5: 177086872 - 177098144 on Build GRCh38
• UniGene ID: Hs.165950
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: FGFR4
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001291980.1	NP_001278909.1	14	1936
	NM_002011.4	NP_002002.3	14	2140
	NM_022963.3	NP_075252.2	12	1858
	NM_213647.2	NP_998812.1	14	2184
	XM_005265838.3	XP_005265895.1	14	2092
	XM_011534464.2	XP_011532766.1	14	2254
	XM_011534465.2	XP_011532767.1	14	2177
GenBank mRNA	AB209631.1	-	10	4261
	AF202063.1	-	12	1841
	AF359246.1	-	10	1461
	AK225280.1	-	14	2098
	AK225909.1	-	14	2098
	AK301169.1	-	14	1903
	BC011847.2	-	14	2170	4121396
	JN007471.1	-	13	1925
	JN007472.1	-	13	1925
	JN007473.1	-	13	1925
	JN007474.1	-	13	1925
	JN007475.1	-	13	1925
	JN007476.1	-	13	1925
	JN007477.1	-	13	1925
	JN007478.1	-	13	1925
	JN007479.1	-	13	1925
	JN007480.1	-	13	1925
	JN007481.1	-	13	1925
	JN007482.1	-	13	1925
	L03840.1	-	14	2095
	M59373.1	-	1	97
	X57205.1	-	13	1980

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_008011, X57236, BC033313, X59927, AK084850, and others.

Matching Taqman Gene Expression Assay:

Hs00242558_m1

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

MAPK cascade
positive regulation of cell proliferation
fibroblast growth factor receptor signaling pathway
positive regulation of gene expression
regulation of extracellular matrix disassembly
regulation of phosphatidylinositol 3-kinase signaling
cell migration
peptidyl-tyrosine phosphorylation
regulation of lipid metabolic process
phosphatidylinositol-3-phosphate biosynthetic process
glucose homeostasis
positive regulation of catalytic activity
positive regulation of GTPase activity
positive regulation of proteolysis
protein autophosphorylation
phosphatidylinositol phosphorylation
phosphatidylinositol-mediated signaling
phosphate ion homeostasis
positive regulation of ERK1 and ERK2 cascade
regulation of bile acid biosynthetic process
response to bile acid
regulation of cholesterol homeostasis
positive regulation of DNA biosynthetic process

Function(s)

protein tyrosine kinase activity
fibroblast growth factor-activated receptor activity
Ras guanyl-nucleotide exchange factor activity
protein binding
ATP binding
heparin binding
1-phosphatidylinositol-3-kinase activity
fibroblast growth factor binding
phosphatidylinositol-4,5-bisphosphate 3-kinase activity