s5258

• Gene Symbol: FOXO1
• Gene Name: forkhead box O1
• Gene Aliases: FKH1, FKHR, FOXO1A
• Chromosome Location: Chr.13: 40555664 - 40666597 on Build GRCh38
• UniGene ID: Hs.370666
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: FOXO1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_002015.3	NP_002006.2	2	1160
	XM_011535008.2	XP_011533310.1	2	1313
	XM_011535010.2	XP_011533312.1	2	3825
GenBank mRNA	AF032885.1	-	2	1160
	AK310511.1	-	2	252
	BC021981.2	-	2	1088	2959021
	BC070065.1	-	2	1151	30345006
	BT007455.1	-	2	775
	BX648278.1	-	2	363
	U02310.1	-	2	781

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001191846, AF247812.

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
blood vessel development
temperature homeostasis
cellular glucose homeostasis
transcription, DNA-templated
protein acetylation
autophagy
apoptotic process
cellular response to DNA damage stimulus
insulin receptor signaling pathway
cellular response to starvation
positive regulation of autophagy
endocrine pancreas development
cellular response to insulin stimulus
negative regulation of stress-activated MAPK cascade
cellular response to oxidative stress
regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter
positive regulation of apoptotic process
negative regulation of apoptotic process
fat cell differentiation
negative regulation of fat cell differentiation
positive regulation of gluconeogenesis
positive regulation of protein catabolic process
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
enamel mineralization
cellular response to hydrogen peroxide
cellular response to cold
cellular response to hyperoxia
cellular response to dexamethasone stimulus
cellular response to nitric oxide
negative regulation of canonical Wnt signaling pathway
neuronal stem cell population maintenance
response to fluoride
regulation of neural precursor cell proliferation
regulation of reactive oxygen species metabolic process
regulation of energy homeostasis

Function(s)

RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcription factor activity, transcription factor binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription coactivator binding
chromatin binding
protein binding
beta-catenin binding
ubiquitin protein ligase binding
sequence-specific DNA binding
protein phosphatase 2A binding