s529408

• Gene Symbol: MECP2
• Gene Name: methyl-CpG binding protein 2
• Gene Aliases: AUTSX3, MRX16, MRX79, MRXS13, MRXSL, PPMX, RS, RTS, RTT
• Chromosome Location: Chr.X: 154021800 - 154097731 on Build GRCh38
• UniGene ID: Hs.200716
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: MECP2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_004992.3	NP_004983.1	4	1975
	XM_005274682.4	XP_005274739.1	5	2049
	XM_006724819.3	XP_006724882.1	4	1726
	XM_011531166.2	XP_011529468.1	3	1862
	XM_017029533.1	XP_016885022.1	7	2475
GenBank mRNA	AF158180.1	-	4	1916
	AJ132917.1	-	3	1824
	GQ203293.1	-	4	1976
	GQ203294.1	-	4	1975
	GQ203295.1	-	4	1977
	GQ896382.1	-	4	1975
	GU479943.1	-	4	1975
	HM020402.1	-	4	1971
	HM156732.1	-	4	1975
	HM156733.1	-	4	1976
	HQ141378.1	-	4	1977
	HQ154629.1	-	5	1635
	X89430.1	-	2	1721

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: AJ132924, AF158181, AJ132922.

Panther Classification:

Molecular Function -

DNA metabolism protein

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
behavioral fear response
response to hypoxia
startle response
neurological system process involved in regulation of systemic arterial blood pressure
regulation of respiratory gaseous exchange by neurological system process
inositol metabolic process
mitochondrial electron transport, ubiquinol to cytochrome c
chromatin silencing
regulation of gene expression by genetic imprinting
transcription, DNA-templated
glutamine metabolic process
cellular biogenic amine metabolic process
synapse assembly
heart development
respiratory gaseous exchange
long-term memory
locomotory behavior
protein localization
glucocorticoid metabolic process
positive regulation of cell proliferation
adult locomotory behavior
visual learning
response to radiation
pathogenesis
post-embryonic development
response to ionizing radiation
response to lead ion
dendrite development
histone methylation
histone acetylation
proprioception
sensory perception of pain
cerebellum development
ventricular system development
negative regulation of histone methylation
cardiolipin metabolic process
response to estradiol
negative regulation of histone acetylation
social behavior
neuron maturation
negative regulation of neuron apoptotic process
regulation of DNA methylation
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
phosphatidylcholine metabolic process
negative regulation of astrocyte differentiation
catecholamine secretion
positive regulation of synapse assembly
excitatory postsynaptic potential
long-term synaptic potentiation

Function(s)

four-way junction DNA binding
DNA binding
transcription factor activity, sequence-specific DNA binding
transcription corepressor activity
mRNA binding
protein binding
transcription factor binding
methyl-CpG binding
double-stranded methylated DNA binding
protein domain specific binding
chromatin DNA binding
siRNA binding
histone deacetylase binding
poly(A) RNA binding
unmethylated CpG binding
protein N-terminus binding