s531163

Gene Symbol:

FGFR1 PLAG1

Gene Name:

fibroblast growth factor receptor 1

PLAG1 zinc finger

Gene Aliases:

BFGFR, CD331, CEK, ECCL, FGFBR, FGFR-1, FLG, FLT-2, FLT2, HBGFR, HH2, HRTFDS, KAL2, N-SAM, OGD, bFGF-R-1

PSA, SGPA, ZNF912

Chromosome Location:

Chr.8: 38411138 - 38468834 on Build GRCh38

Chromosome Location:

Chr.8: 56160909 - 56211327 on Build GRCh38

UniGene ID:

Hs.264887

Hs.14968

Species:

Human

Species Specific ID (Flybase ID):

-

-

siRNA Details

Gene Symbol: FGFR1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001174063.1	NP_001167534.1	2	880
	NM_001174064.1	NP_001167535.1	2	880
	NM_001174065.1	NP_001167536.1	2	200
	NM_001174066.1	NP_001167537.1	2	200
	NM_001174067.1	NP_001167538.1	3	360
	NM_015850.3	NP_056934.2	2	880
	NM_023105.2	NP_075593.1	2	880
	NM_023106.2	NP_075594.1	2	880
	NM_023110.2	NP_075598.2	2	880
	XM_006716303.2	XP_006716366.1	2	681
	XM_006716304.1	XP_006716367.1	2	197
	XM_006716306.2	XP_006716369.1	2	681
	XM_006716307.1	XP_006716370.1	2	197
	XM_006716310.2	XP_006716373.1	2	681
	XM_006716311.1	XP_006716374.1	2	79
	XM_006716312.1	XP_006716375.1	2	149
	XM_006716313.2	XP_006716376.1	2	681
	XM_006716314.1	XP_006716377.1	2	159
	XM_011544443.2	XP_011542745.1	2	186
	XM_011544444.1	XP_011542746.1	2	181
	XM_011544445.2	XP_011542747.1	2	194
	XM_011544446.2	XP_011542748.1	2	181
	XM_011544447.2	XP_011542749.1	2	181
	XM_011544448.1	XP_011542750.1	2	52
	XM_011544449.1	XP_011542751.1	2	52
	XM_011544450.2	XP_011542752.1	2	52
	XM_011544452.2	XP_011542754.1	2	275
	XM_017013219.1	XP_016868708.1	2	188
	XM_017013220.1	XP_016868709.1	2	181
	XM_017013221.1	XP_016868710.1	3	390
	XM_017013222.1	XP_016868711.1	2	681
	XM_017013223.1	XP_016868712.1	2	197
	XM_017013224.1	XP_016868713.1	2	681
	XM_017013225.1	XP_016868714.1	2	164
	XM_017013226.1	XP_016868715.1	2	52
	XM_017013227.1	XP_016868716.1	2	52
	XM_017013228.1	XP_016868717.1	2	681
	XM_017013231.1	XP_016868720.1	2	279
GenBank mRNA	AB208919.1	-	2	667
	AK222718.1	-	2	679
	AK223126.1	-	2	681
	AK291754.1	-	2	79
	AK292470.1	-	2	200
	AK309947.1	-	3	239
	BC015035.1	-	3	608	3911101
	BC018128.1	-	2	644	3896359
	BC091494.1	-	1	17	30387634
	EF525171.1	-	2	47
	FJ809916.1	-	2	880
	FJ809917.1	-	2	880
	M34185.1	-	2	193
	M34186.1	-	2	464
	M34187.1	-	2	354
	M34188.1	-	2	460
	M37722.1	-	2	166
	M60485.1	-	3	609
	X57119.1	-	2	100
	X57120.1	-	2	100
	X57121.1	-	2	100
	X57122.1	-	2	100
	X66945.1	-	2	664

Gene Symbol: PLAG1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
GenBank mRNA	EF525170.1	-		46

More Information

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
MAPK cascade
skeletal system development
angiogenesis
ureteric bud development
in utero embryonic development
organ induction
neuron migration
positive regulation of mesenchymal cell proliferation
chondrocyte differentiation
transcription, DNA-templated
protein phosphorylation
sensory perception of sound
positive regulation of cell proliferation
fibroblast growth factor receptor signaling pathway
positive regulation of phospholipase activity
positive regulation of phospholipase C activity
positive regulation of neuron projection development
regulation of phosphatidylinositol 3-kinase signaling
positive regulation of phosphatidylinositol 3-kinase signaling
cell migration
peptidyl-tyrosine phosphorylation
stem cell population maintenance
motogenic signaling involved in postnatal olfactory bulb interneuron migration
ventricular zone neuroblast division
embryonic limb morphogenesis
midbrain development
neuron projection development
fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development
phosphatidylinositol-3-phosphate biosynthetic process
inner ear morphogenesis
outer ear morphogenesis
middle ear morphogenesis
chordate embryonic development
positive regulation of MAP kinase activity
positive regulation of MAPK cascade
positive regulation of GTPase activity
regulation of cell differentiation
positive regulation of neuron differentiation
negative regulation of osteoblast differentiation
positive regulation of cell cycle
protein autophosphorylation
phosphatidylinositol phosphorylation
phosphatidylinositol-mediated signaling
paraxial mesoderm development
regulation of lateral mesodermal cell fate specification
cell maturation
skeletal system morphogenesis
mesenchymal cell differentiation
regulation of sensory perception of pain
positive regulation of cardiac muscle cell proliferation
auditory receptor cell development
branching involved in salivary gland morphogenesis
lung-associated mesenchyme development
regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling
regulation of stem cell proliferation
positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway
positive regulation of endothelial cell chemotaxis to fibroblast growth factor
regulation of extrinsic apoptotic signaling pathway in absence of ligand

Function(s)

glycoprotein binding
protein tyrosine kinase activity
fibroblast growth factor-activated receptor activity
Ras guanyl-nucleotide exchange factor activity
protein binding
ATP binding
heparin binding
1-phosphatidylinositol-3-kinase activity
fibroblast growth factor binding
protein complex binding
identical protein binding
protein homodimerization activity
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
cell adhesion molecule binding