s532203

• Gene Symbol: NOTCH3
• Gene Name: notch 3
• Gene Aliases: CADASIL, CADASIL1, CASIL, IMF2, LMNS
• Chromosome Location: Chr.19: 15159633 - 15200981 on Build GRCh38
• UniGene ID: Hs.8546
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: NOTCH3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000435.2	NP_000426.2	25, 26	4820
	XM_005259924.4	XP_005259981.1	24, 25	4603
GenBank mRNA	U97669.1	-	25, 26	4822

More Information

Panther Classification:

Molecular Function -

cell adhesion molecule

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
Notch signaling pathway
Notch receptor processing
forebrain development
negative regulation of neuron differentiation
positive regulation of transcription from RNA polymerase II promoter
positive regulation of smooth muscle cell proliferation
neuron fate commitment
artery morphogenesis
glomerular capillary formation
cell-cell adhesion

Function(s)

receptor activity
calcium ion binding
protein binding
enzyme binding
cadherin binding involved in cell-cell adhesion